Zobrazeno 1 - 10
of 34
pro vyhledávání: '"I.C. Felkner"'
Autor:
I.C. Felkner, B.E. Worthy
Publikováno v:
The Science of the total environment. 112(2-3)
A new approach has been developed for assessing the toxicity and the metabolism of Group IV compounds and for other toxic substances that may interact with them at the molecular level. The approach is based upon the selective responses of sensitive b
Publikováno v:
Journal of Agricultural and Food Chemistry. 29:268-271
Autor:
I.C. Felkner
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 42:175-179
Summary A procedure was developed to select for specific mutations obtained by means of transformation with DNA previously exposed to potentially dangerous chemical compounds. The 70% co-transformation of hisB and trpC genes in Bacillus subtilis prov
Publikováno v:
Chemical Speciation & Bioavailability. 1:79-92
New approaches for assessing the toxicity of organotin chemical species have been developed. These approaches are based upon the selective responses of sensitive biodetectors whose chemical and molecular interactions with a wide variety of toxicants
Autor:
I.C. Felkner, A.D. Laumbach
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 15:233-245
When cultures of Bacillus subtilis were treated with 4-nitroquinoline-1-oxide (4NQO), this compound complexed with their DNA. Strains with a Rec + phenotype recovered from this treatment, whereas Hcr − , Rec − mutants did not. Those strains able
Publikováno v:
Mutation research. 68(1)
Mutagenic, DNA-damaging, and in vivo alteration of DNA have been demonstrated for 1,2-dimethylhydrazine (DMH), a potent inducer of adenocarcinomas of the large intestine and colon of rats. These activities are pH-dependent, with 6.5 giving optimum re
Publikováno v:
Mutation research. 71(2)
The active pure compounds of 4 pesticides were tested for DNA-damaging and mutagenic activity in Bacillus subtilis and Salmonella typhimurium tester strains. Included were zinc ethylenebisdithiocarbamate (dithane), 1,2-dihydropyridazine-3,6-dione (ma
Autor:
T.S. Matney, I.C. Felkner
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 31:326-327
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