Zobrazeno 1 - 10
of 28
pro vyhledávání: '"I.Arthur Michaelson"'
Publikováno v:
Life Sciences. 35:1921-1930
The determination of glutamic and gamma-aminobutyric acids in rat brain regions by derivatization with 0-phthaldialdehyde-thiol, isocratic separation by liquid chromatography, and quantification by electrochemical detection provides a simple and prec
Publikováno v:
Pharmacology Biochemistry and Behavior. 7:37-42
Rats exposed to lead via maternal milk were tested at various stages of development on a number of behavioral tasks. Beginning at paturition, the dams were given either tap water, 0.02%, or 0.10% lead acetate in the drinking water. Pups from all thre
Publikováno v:
Toxicology and Applied Pharmacology. 84:400-411
The effect of inorganic lead in vitro in several aspects of [3H]dopamine release from superfused rat striatal synaptosomes was examined. Under conditions of spontaneous release, lead (1-30 microM) induced dopamine release in a concentration-dependent
Publikováno v:
Toxicology and Applied Pharmacology. 45:119-129
The effect of chronic lead exposure on oxidative hemolysis and on biochemical defense mechanisms against such hemolysis was examined. The interaction between lead (Pb) and phenylhydrazine (PHZ) was studied using four groups of adult male rats treated
Publikováno v:
Pharmacology Biochemistry and Behavior. 10:95-104
Three interrelated studies were conducted to examine the locomotor activity of lead-exposed mice. The effects of lead were examined as a function of the dose and duration of exposure. Exposure during the first three weeks occurred via the maternal mi
Publikováno v:
Biochemical Pharmacology. 20:2091-2094
Autor:
Petrea Z. Coffman, I.Arthur Michaelson
Publikováno v:
Biochemical Pharmacology. 16:1636-1641
Publikováno v:
Life Sciences. 13:417-428
Lead poisoning was produced in suckling rats by lead fed to lactating mother rats being transmitted to newborns via maternal milk. The brain of 25 day old lead poisoned rats contained 6.0 to 12.5 ppm lead. Zinc was depressed 56% (cerebral cortex), 45
Publikováno v:
Biochemical Pharmacology. 17:2435-2441
The concentration of histamine and spermidine in fifteen different regions of rhesus monkey ( Macaco mulatta ) brain were studied using the O -phthaldialdehyde fluorometric method. The highest levels for histamine were found in the hypothalamus. Sper
Autor:
Gordon Dowe, I.Arthur Michaelson
Publikováno v:
Biochemical Pharmacology. 12:949-956
The subcellular distribution of histamine has been analysed in guinea pig whole brain, dog hypothalamus and dog pituitary gland. In whole brain, histamine is found in both the nuclear and crude mitochondrial fractions. In brain tissue lacking mast ce