Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice

Autor: Pauline I.A. de Bruijn, Mads V. Sorensen, Markus Bleich, Helle A. Praetorius, Iben Skov Jensen, Jens Leipziger, Casper Larsen

Publikováno v: Larsen, C K, Jensen, I S, Sørensen, M V, de Bruijn, P I, Bleich, M, Prætorius, H & Leipziger, J 2016, ' Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice ', American Journal of Physiology: Renal Physiology, vol. 310, no. 10, pp. F1035-46 . https://doi.org/10.1152/ajprenal.00010.2016

The kidney is the primary organ ensuring K+homeostasis. K+is secreted into the urine in the distal tubule by two mechanisms: by the renal outer medullary K+channel (Kir1.1) and by the Ca2+-activated K+channel (KCa1.1). Here, we report a novel knockou

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https://pure.au.dk/portal/da/publications/hyperaldosteronism-after-decreased-renal-k-excretion-in-kcnmb2-knockout-mice(18aca309-895d-42df-84b7-608f3f62ad3e).html

[Ca2+]i Oscillations and IL-6 Release Induced by α-Hemolysin from Escherichia coli Require P2 Receptor Activation in Renal Epithelia

Autor: Steen K. Fagerberg, Mette G. Christensen, Jens Leipziger, Randi G. Bjaelde, Pauline I.A. de Bruijn, Helle Jakobsen, Marianne Skals, Helle A. Praetorius

Publikováno v: Christensen, M, Fagerberg, S K, de Bruijn, P I A, Bjælde, R G, Jakobsen, H, Leipziger, J G, Skals, M G & Prætorius, H 2015, ' [Ca2+]i oscillations and IL-6 release induced by alpha-hemolysin from Escherichia coli require P2 receptor activation in renal epithelia ', Journal of Biological Chemistry, vol. 290, no. 23, pp. 14776-84 . https://doi.org/10.1074/jbc.M115.639526

Urinary tract infections are commonly caused by α-hemolysin (HlyA)-producing Escherichia coli. In erythrocytes, the cytotoxic effect of HlyA is strongly amplified by P2X receptors, which are activated by extracellular ATP released from the cytosol o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b1c5a147b4f9904e85e0d43d8b669c
https://pubmed.ncbi.nlm.nih.gov/25911098

Trivalent inactivated subunit influenza vaccine Influvac: 25-Year experience of safety and immunogenicity

Autor: Katinka Giezeman, Jozef J.P. Nauta, I.A. de Bruijn, A. M. Palache

Publikováno v: Vaccine. 27(18)

Between 1982 and 2006, 76 clinical studies (including the annual update studies required for licensing in Europe) were performed with the trivalent inactivated subunit influenza vaccine Influvac. In all, 6415 subjects were vaccinated, of whom 5034 we

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https://pubmed.ncbi.nlm.nih.gov/19368782

Zijn er immunologische bezwaren tegen griepvaccinatie bij werknemers die niet tot een risicogroep behoren?

Autor: E. J. Remarque, I.A. de Bruijn

Publikováno v: Vademecum permanente nascholing huisartsen ISBN: 9789031388073

Er zijn geen immunologische bezwaren tegen het vaccineren van werknemers die niet tot een risicogroep behoren. Personen met een overgevoeligheid voor kippeneieren dienen echter niet te worden gevaccineerd. Het vaccin wordt in kippeneieren geproduceer

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https://doi.org/10.1007/978-90-313-8808-0_1012

Clinical experience with inactivated, virosomal influenza vaccine

Autor: Jozef J.P. Nauta, Gerez Lisya, W.C.M. Cramer, A. M. Palache, I.A. de Bruijn

Publikováno v: Vaccine. 23

Current available influenza vaccines are safe and effective in preventing influenza. Nevertheless, there is a need for influenza vaccines with improved efficacy in the elderly. This need is underscored by both the observation that influenza has a maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2684d10d844094b527962bd6f590ea9b
https://pubmed.ncbi.nlm.nih.gov/16005120