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Autor:
I. Yu. Ushakov, V. Kh. Kravtsov, T. A. Kabanova, V. I. Pavlovskii, E. I. Khalimova, S. A. Andronati
Publikováno v:
Pharmaceutical Chemistry Journal. 49:592-597
Interaction of 3-chloro-5-aryl-1,2-dihydro-3H-1,4-benzodiazepines with aromatic amines was used to synthesize 3-arylamino-1,2-dihydro-3H-1,4-benzodiazepin-2-ones with analgesic activity in the acetate acid writing test (ED50 0.007 – 3.2 mg).