Contents, Vol. 97, 1992

Autor: Ernst Gleichmann, Erika Schläpfer, Yutaka Morita, José Angel Gonzalo, Jan de Groot, Mahfuz B. Khan, David Nadal, I. Kimber, Stefan A. Cohen, Dagmar Haas-Raida, S. Abe, Wijnand Eduard, Ute Bömer, Georg Wick, Hisashi Ohkuni, A.H.W.M. Schuurs, D.A. Basketter, Nobuo Watanabe, Motohiro Kurosawa, Chaoyuan Chen, Rik J. Scheper, G. Wick, John B. Zabriskie, Peter Kind, Dagmar Boden, Toshiaki Takaishi, Ingrid M.W. van Hoogstraten, J.A. Mitchell, Oichi Kawanami, Murray W. Stinson, Koji Ito, R.J. Dearman, Mary E. von Blomberg, Guido Kroemer, D. Kraft, Miguel Parreira Soares, Pearay L. Ogra, R. Valenta, K. Katayama, I. Yamatsu, Hideo Tsukagoshi, Y. Sakuma, Hans-Christian Schuppe, Ram G. Navalkar, Johanna Kulig, Viviana Chavez, Masao Yamaguchi, Ken Ohta, Georg Kraal, S. Katayama, Kazuo Motoyoshi, Koichi Hirai, Hervé Bazin, Masahiro Furuya, J. Gruber, Leon P. Bignold, Susan D. Rogers, C. Ebner, Basab K. Mookerjee, S. Vrtala, Shinsuke Tanaka, Adrian O. Vladutiu, Boris Albini, Yuko Todome, Damien G. Harkin, Satoshi Fujikawa, Rajashri G. Deshpande, H. Dietrich, Finn Levy, Katsuyuku Fujii, Per Sandven, Yuji Shimizu, H. Tsunoda, Eduardo Cuende, Manabu Mizuse, Shuji Suzuki, José Enrique Alés-Martínez, O. Scheiner, Carlos Martínez-A

Publikováno v: International Archives of Allergy and Immunology. 97:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc7329661e24fee751107415af5721fa
https://doi.org/10.1159/000236128

E5531, a synthetic non-toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide

Autor: T, Kawata, J R, Bristol, D P, Rossignol, J R, Rose, S, Kobayashi, H, Yokohama, A, Ishibashi, W J, Christ, K, Katayama, I, Yamatsu, Y, Kishi

Publikováno v: British journal of pharmacology. 127(4)

1. The major pathological responses to Gram-negative bacterial sepsis are triggered by endotoxin or lipopolysaccharide. As endotoxin is shed from the bacterial outer membrane, it induces immunological responses that lead to release of a variety of cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8424058107a931cacf166bcc701c60c
https://pubmed.ncbi.nlm.nih.gov/10433491

Protective effects of (2E)-3-[5-(2,3-dimethoxy-6-methyl-1,4- benzoquinoyl)]-2-nonyl-2-propenoic acid on endotoxin-mediated hepatitis in mice

Autor: J, Nagakawa, I, Hishinuma, K, Miyamoto, K, Hirota, S, Abe, T, Yamanaka, K, Katayama, I, Yamatsu

Publikováno v: The Journal of pharmacology and experimental therapeutics. 262(1)

E3330 [(2E)-3-[5-(2,3-dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2- propenoic acid] is a newly synthesized hepatoprotective quinone derivative. We examined the protective effects and possible mechanism of action of E3330 in three different endotox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b8b0cf6eb71fd9f25d23701ec7e9cf70
https://pubmed.ncbi.nlm.nih.gov/1625194

Activity of a novel thienodiazepine derivative as a platelet-activating factor antagonist in guinea pig lungs. Effects on platelet-activating factor and allergen induced eosinophil accumulation

Autor: H, Tsunoda, Y, Sakuma, M, Shirato, H, Obaishi, K, Harada, K, Yamada, N, Shimomura, Y, Machida, I, Yamatsu, K, Katayama

Publikováno v: Arzneimittel-Forschung. 41(3)

Platelet-activating factor (PAF) inhalation in guinea pigs caused a significant increase in the number of eosinophils recovered from bronchoalveolar lavage fluid (BALF). Oral administration of (S)-(+)-6-(2-chlorophenyl)-3-cyclopropanecarbonyl-8,11- d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::798114328a7b02fd9ea2ea4994f75f12
https://pubmed.ncbi.nlm.nih.gov/1867658

THE NEWLY SYNTHESIZED COMPOUND E-5510 IS A HIGHLY POTENT ANTIPLATELET AGENT

Autor: K Harada, T Fujimori, M Kogushi, I Yamatsu, Y Ikeda

Publikováno v: XIth International Congress on Thrombosis and Haemostasis.

Our newly synthesized compound, 4-cyano-5,5-bis(methoxy-phenyl)-4-pentenoic acid (E-5510) has highly potent antiplatelet activity. In this paper, the effects of E-5510 on platelet functions in vitro and ex vivo in human and in various experimental an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::310a1594c3c79c503b4fe808fdedc60e
https://doi.org/10.1055/s-0038-1643428