Výsledky vyhledávání

Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven hepatic lipogenesis

Autor: Peter J. Espenshade, Gerald Hoefler, Silvia Schauer, Rolf Breinbauer, Paul Vesely, Paola Peña de la Sancha, Wolfgang Sattler, Helga Reicher, Martina Schweiger, Rudolf Zechner, Beatrix I. Wieser

Sterol Regulatory Element-Binding Protein-1c (SREBP-1c) is translated as an inactive precursor-protein that is proteolytically activated to promote fatty-acid (FA) biosynthesis, when unsaturated (u)FAs are scarce. During fasting, however, lipogenesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::694ac37d960d4cde3b360afb718fc5cc
https://doi.org/10.1101/2020.11.02.363440

Zobrazit plný text záznamu

Intestine‐Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet‐Induced Liver Steatosis and Obesity

Autor: Thomas O. Eichmann, Jan B. van Klinken, Pia Benedikt, Christina Leopold, Lisa Katharina Maresch, Gabriele Schoiswohl, Ursula Feiler, C. Lackner, Guenter Haemmerle, Thomas Rülicke, Sandra Eder, Tarek Moustafa, Ulrike Taschler, Beatrix I. Wieser, Stephanie Kolleritsch, Gerald Hoefler, Dagmar Kratky, Kathrin A. Zierler

Publikováno v: Hepatology Communications, 3(2), 227-245. JOHN WILEY & SONS LTD
Hepatology Communications

Murine hepatic carboxylesterase 2c (Ces2c) and the presumed human ortholog carboxylesterase 2 (CES2) have been implicated in the development of nonalcoholic fatty liver disease (NAFLD) in mice and obese humans. These studies demonstrated that Ces2c h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2f2f014ca4eb932afae00994cbf609
https://doi.org/10.1002/hep4.1292

Zobrazit plný text záznamu

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation

Autor: Laura, Pajed, Carina, Wagner, Ulrike, Taschler, Renate, Schreiber, Stephanie, Kolleritsch, Nermeen, Fawzy, Isabella, Pototschnig, Gabriele, Schoiswohl, Lisa-Maria, Pusch, Beatrix I, Wieser, Paul, Vesely, Gerald, Hoefler, Thomas O, Eichmann, Robert, Zimmermann, Achim, Lass

Publikováno v: The Journal of Biological Chemistry

Lysosomal acid lipase (LAL) hydrolyzes cholesteryl ester (CE) and retinyl ester (RE) and triglyceride (TG). Mice globally lacking LAL accumulate CE most prominently in the liver. The severity of the CE accumulation phenotype progresses with age and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d316a73aa697d182aeb83ffefffbed5
https://pubmed.ncbi.nlm.nih.gov/31023823

Zobrazit plný text záznamu

The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells

Autor: Alexandra Bertsch, Andrea Olschewski, Thomas Züllig, Elvira Stacher, Beatrix I. Wieser, Harald Köfeler, Andelko Hrzenjak, Ruth Prassl, Barbara Hinteregger, Alexander Triebl, Martin Trötzmüller, Petra Leko, Alessandro Valli, Gabriele Grasmann, Horst Olschewski, Adrian L. Harris, Katharina Leithner

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 115(24)

Cancer cells are reprogrammed to consume large amounts of glucose to support anabolic biosynthetic pathways. However, blood perfusion and consequently the supply with glucose are frequently inadequate in solid cancers. PEPCK-M (PCK2), the mitochondri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596be97d36fb685d7fa579d0dac50363
http://ora.ox.ac.uk/objects/uuid:

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Changes in ductus venosus flow profile in twin-twin transfusion syndrome: role in risk stratification

Autor: C, Wohlmuth, F A, Osei, K J, Moise, I, Wieser, A, Johnson, R, Papanna, M, Bebbington, H M, Gardiner

Publikováno v: Ultrasound in obstetricsgynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 48(6)

To evaluate changes in ductus venosus (DV) waveforms and the timing of these changes in twin-twin transfusion syndrome (TTTS), to relate these to disease severity and to assess the clinical applicability of the suggested measurements in the predictio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f6053cc9c262db0e2a4ffd1d9aea1ada
https://pubmed.ncbi.nlm.nih.gov/26989864

Zobrazit plný text záznamu

Information Technology (IT) in radiology tele-consultation

Autor: W. I. Wieser

Publikováno v: Digital (R)Evolution in Radiology ISBN: 9783211208151
Digital (R)Evolution in Radiology ISBN: 9783709137093

IT systems are increasingly used in radiology to improve and intensify medical communication. The principal areas of application are central diagnosis, expert consultation, and tele-conferencing.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825e1083fbc62c049abfa7114d807f5e
https://doi.org/10.1007/3-211-37761-1_23

Zobrazit plný text záznamu

Injuries due to letter bombs

Autor: J, Missliwetz, B, Schneider, H, Oppenheim, I, Wieser

Publikováno v: Journal of forensic sciences. 42(6)

In Austria in late 1993 ten letter bombs were sent to outstanding persons who have been engaged in the care of foreigners. Four of these bombs detonated, when they were opened by the addressee. The remaining six bombs were discovered in time and coul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71f4681c7df70221a2f67f80ffdbb358
https://pubmed.ncbi.nlm.nih.gov/9397543

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání