Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO.

Autor: A V Ramanan, L V Hampson, H Lythgoe, A P Jones, B Hardwick, H Hind, B Jacobs, D Vasileiou, I Wadsworth, N Ambrose, J Davidson, P J Ferguson, T Herlin, A Kavirayani, O G Killeen, S Compeyrot-Lacassagne, R M Laxer, M Roderick, J F Swart, C M Hedrich, M W Beresford

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0215739 (2019)

IntroductionChronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder primarily affecting children and adolescents. It can lead to chronic pain, bony deformities and fractures. The pathophysiology of CNO is incompletely unders

Externí odkaz: https://doaj.org/article/9874f4e367b04962a6d22b2eba990e3a

187O Capivasertib and fulvestrant for patients (pts) with aromatase inhibitor (AI)-resistant HR+/HER2– advanced breast cancer (ABC): Subgroup analyses from the phase III CAPItello-291 trial

Autor: M. Oliveira, H.S. Rugo, S.J. Howell, F. Dalenc, J. Cortés, H.L. Gomez Moreno, X. Hu, K. Jhaveri, S. Loibl, S. Morales, M. Okera, Y.H. Park, J. Sohn, E. Tokunaga, L. Zhukova, I. Wadsworth, G. Schiavon, A. Foxley, N. Turner

Publikováno v: ESMO Open. 8:101376

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69b5ec36d8211c821490afe63f2e0d82
https://doi.org/10.1016/j.esmoop.2023.101376

Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design:An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO

Autor: S. Compeyrot-Lacassagne, T. Herlin, Athimalaipet V Ramanan, Michael W. Beresford, R. M. Laxer, A. Kavirayani, Ashley P Jones, J. F. Swart, Ben Hardwick, D. Vasileiou, Hanna Lythgoe, Lisa V. Hampson, H. Hind, I. Wadsworth, B. Jacobs, J Davidson, O. G. Killeen, Nicola Ambrose, Polly J. Ferguson, Christian M. Hedrich, Marion Roderick

Publikováno v: Ramanan, A V, Hampson, L V, Lythgoe, H, Jones, A P, Hardwick, B, Hind, H, Jacobs, B, Vasileiou, D, Wadsworth, I, Ambrose, N, Davidson, J, Ferguson, P J, Herlin, T, Kavirayani, A, Killeen, O G, Compeyrot-Lacassagne, S, Laxer, R M, Roderick, M, Swart, J F, Hedrich, C M & Beresford, M W 2019, ' Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design : An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO ', PLOS ONE, vol. 14, no. 6, e0215739 . https://doi.org/10.1371/journal.pone.0215739
PLOS ONE
PLoS ONE, Vol 14, Iss 6, p e0215739 (2019)
PLoS ONE
Ramanan, A V, Hampson, L V, Lythgoe, H, Jones, A P, Hardwick, B, Hind, H, Jacobs, B, Vasileiou, D, Wadsworth, I, Ambrose, N, Davidson, J, Ferguson, P J, Herlin, T, Kavirayani, A, Killeen, O G, Compeyrot-Lacassagne, S, Laxer, R M, Roderick, M, Swart, J F, Hedrich, C M & Beresford, M W 2019, ' Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design : An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO ', PLoS ONE, vol. 14, no. 6, e0215739 . https://doi.org/10.1371/journal.pone.0215739
PLoS ONE, 14(6). Public Library of Science

IntroductionChronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder primarily affecting children and adolescents. It can lead to chronic pain, bony deformities and fractures. The pathophysiology of CNO is incompletely unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a642bb5582c0bf714a811ba267fba0
https://pure.au.dk/portal/da/publications/defining-consensus-opinion-to-develop-randomised-controlled-trials-in-rare-diseases-using-bayesian-design(6579e586-a08f-4d6e-9fb1-7fe16a0ee628).html

Investigation of substoichiometric titanium nitride grown by unbalanced magnetron sputtering

Autor: S Yang, D.B. Lewis, Wolf-Dieter Münz, I. Wadsworth, J.S. Brooks, J. Cawley

Publikováno v: Surface and Coatings Technology. 131:228-233

TiN x (stoichiometric factor, x =0.1–0.4) films were deposited at a substrate temperature typically of 480°C using an industrial-sized multi-target PVD coating machine. The stoichiometric factor, x , depended on the manner of substrate rotation as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84c77896c8a83a17b11afb783d457a9a
https://doi.org/10.1016/s0257-8972(00)00828-8

Tribological investigation of TiAlCrN and TiAlN/CrN coatings grown by combined steered-arc/unbalanced magnetron deposition

Autor: Wolf-Dieter Münz, L.A. Donohue, W.M. Rainforth, I. Wadsworth, Quanshun Luo

Publikováno v: Vacuum. 53:123-126

The dry sliding wear of monolayer TiAlCrN and multilayer TiAlN/CrN coatings has been investigated against a BM2 tool steel counterface. The coatings were deposited on a BM2 tool steel substrate by combined steered-arc/unbalanced-magnetron deposition.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04b9d438397eca88e9d9ea69ca28ccac
https://doi.org/10.1016/s0042-207x(98)00406-0