Zobrazeno 1 - 10
of 19
pro vyhledávání: '"I. W. Reimann"'
Autor:
U, Klotz, I W, Reimann
Publikováno v:
Pharmaceutical research. 1(2)
H2-receptor blocking agents, such as cimetidine, ranitidine or oxmetidine, are consumed in large amounts often together with a variety of other drugs. There is increasing evidence that cimetidine interferes with the hepatic elimination of several dru
Autor:
K. Schaffler, I. W. Reimann, Werner Herrmann, J. P. Leonard, M. Jobert, M. Böttcher, H. Ott, C. H. Wauschkuhn, B. Dietrich, M. Versavel, B. Gallhofer, Hartmut Schulz, J. Oldigs-Kerber
Publikováno v:
Klinische Neurophysiologie. 27:55-58
Publikováno v:
Neuropsychobiology. 33:160-163
The comparison of two different modes of data processing and two different approaches to statistical testing both applied to the same set of EEG recordings was the main objective of this pharmacological study. Brofaromine (CGP 11,305 A), a new select
Publikováno v:
European Journal of Clinical Pharmacology. 42:137-141
The pressor effect of intravenous tyramine (TYR) and noradrenaline (NA) has been evaluated, respectively, in 157 tests in 19 healthy unmedicated subjects, and in 202 tests in 24 similar subjects, all of whom took part in greater than or equal to 3 te
Publikováno v:
European Journal of Clinical Pharmacology. 44:93-95
The optically active isomers of the racemic tetracyclic antidepressant oxaprotiline, R (-) oxaprotiline CGP 12,103 A (levoprotiline) and the S (+) oxaprotiline CGP 12,104 A, have been used as tools for a methodological Phase I study. Only the S (+) e
Publikováno v:
Biopharmaceuticsdrug disposition. 13(2)
To investigate the pharmacokinetics and the disposition of levoprotiline after i.v. and p.o. administration and to assess the absolute bioavailability, 12 healthy volunteers (11 women, 1 man) were given a 10 min i.v. infusion of 15 mg and a p.o. dose
Publikováno v:
European Neuropsychopharmacology. 1:476
Publikováno v:
European Journal of Clinical Pharmacology. 28:273-277
In a placebo controlled, single blind, randomized cross over study catecholamines (CA) and renin activity (PRA) in plasma were measured in 2 female and 4 male healthy volunteers, at rest in the supine position, following a single intravenous injectio
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 9(10)
The specific alpha 2-adrenoceptor binding (Bmax and KD) of (3H-methyl)yohimbine to intact platelets of healthy young volunteers was not significantly different in 7 males and 7 females. Its extent was not dependent on the menstrual cycle. The intrain
Publikováno v:
Arzneimittel-Forschung. 37(10)
2-Phenylpyrazolo[4,3-c]quinolin-3(5H)-one (CGS 8216) is pharmacologically characterized as benzodiazepine antagonist with low inverse agonistic effects. Single oral doses up to 650 mg and subchronic doses up to 100 mg daily for seven days are well to