Zobrazeno 1 - 5
of 5
pro vyhledávání: '"I. W. Harman"'
Publikováno v:
Gut. 34:156-160
The potential involvement of neutrophils in the pathogenesis of indomethacin induced ulceration of the gastric antrum in the re-fed rat was studied. Indomethacin was associated with a time dependent increase in the extent and severity of ulceration,
Publikováno v:
Agents and actions. 43(1-2)
We have previously suggested (Trevethick et al., Gut 34, 156-160) that indomethacin-induced ulceration of the rat gastric antrum may be a neutrophil-dependent process. Accordingly, in this study we have used an anti-neutrophil serum (ANS) to investig
Publikováno v:
Agents and actions. 41(3-4)
The potential involvement of leukotrienes in the pathogenesis of indomethacin-induced ulceration of the rat gastric antrum has been studied. Pretreatment with the leukotriene biosynthesis inhibitor, MK886 (30 mg/kg p.o.), inhibited the increases in b
Autor:
I W Harman, N W Spurling, P A Fluck, J L Cook, D Poynter, S.A.M. Selway, R. A. Harcourt, Ainge G, C. R. Pick
Publikováno v:
Gut. 26:1284-1295
The oral administration of loxtidine, a potent histamine H2-antagonist, to a total of 378 rats at doses of 50, 185, or 685 mg/kg/day for 116 weeks resulted in the late formation of carcinoid tumours of the gastric fundus. The first such tumour was de
Autor:
G. G. Patterson, R. M. Atkinson, I. W. Harman, J. M. Wheeldon, D. A. H. Pratt, R. D. Foord, K. Capel-Edwards
Publikováno v:
Infection. 8(1)
The neophrotoxic effect on rats of once daily treatment with 40 or 45 mg gentamicin/kg/day for ten days was substantially reduced by administration of 4 g cefuroxime/kg/day, either at the same time or eight hours later. This dosage of cefuroxime was