Zobrazeno 1 - 10
of 708
pro vyhledávání: '"I. Virag"'
Autor:
K’Shylah S. Whitehurst, Victoria A. Chan, Heather K. Estes, Smrithi Valsaraj, Susan Kent, Uma M. Sharma, R. Christopher Chase, Maliha Bhuiyan, Jitka A. I. Virag
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5811 (2020)
Background: EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at th
Externí odkaz:
https://doaj.org/article/e2585a46ec274b36a5738dae1d3628c5
Autor:
Jitka A. I. Virag, Robert M Lust
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Components of circadian rhythm maintenance, or clock genes, are found in all peripheral tissues, including the heart, and influence such diverse phenomena as cytokine expression immune cells, metabolic activity of cardiac myocytes, and vasodilator re
Externí odkaz:
https://doaj.org/article/356ae65670324652822c3efe34fd36b4
Autor:
Jitka A. I. Virag
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
EphrinA1-EphA-receptor signaling is protective during myocardial infarction (MI). The EphA2-receptor (EphA2-R) potentially mediates cardiomyocyte survival. To determine the role of the EphA2-R in acute non-reperfused myocardial injury in vivo, infarc
Externí odkaz:
https://doaj.org/article/4ab65ee74c6e4cf0a832228f34d9a372
Autor:
Uma M Sharma, R Christopher Chase, Jitka A. I. Virag, Susan D. Kent, Victoria A Chan, Maliha Bhuiyan, Smrithi Valsaraj, K'Shylah S Whitehurst, Heather K Estes
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5811, p 5811 (2020)
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5811, p 5811 (2020)
Background: EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc3065f42b098b9a0136cc7a6ee6b16
https://pubmed.ncbi.nlm.nih.gov/32823610
https://pubmed.ncbi.nlm.nih.gov/32823610
Publikováno v:
Journal of biomechanics. 113
Soft biological tissues demonstrate strong time-dependent mechanical behavior, arising from their intrinsic viscoelasticity and fluid flow-induced poroelasticity. It is increasingly recognized that time-dependent mechanical properties of soft tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c7bc56d5a2bc68ef4cede7775b690a
https://pubmed.ncbi.nlm.nih.gov/33176223
https://pubmed.ncbi.nlm.nih.gov/33176223
Autor:
Robert M. Hughes, Jitka A. I. Virag
Publikováno v:
Pharmaceuticals, Vol 13, Iss 112, p 112 (2020)
Pharmaceuticals
Pharmaceuticals
Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e8483aeccd9781e52af88873af4559
https://www.mdpi.com/1424-8247/13/6/112
https://www.mdpi.com/1424-8247/13/6/112
Autor:
Jitka A. I. Virag, Kimberly A. Kew, Lisandra E. de Castro Brás, Shaun P. Reece, Justin Parks, Maria J. Torres, Sky W Reece, Stephan Lefcoski
Publikováno v:
Journal of the American Society for Mass Spectrometry
EphrinA1 is a tyrosine kinase receptor localized in the cellular membrane of healthy cardiomyocytes, the expression of which is lost upon myocardial infarction (MI). Intra-cardiac injection of the recombinant form of ephrinA1 (ephrinA1-Fc) at the tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d721901b8cb22082c3076f62ec428cff
https://doi.org/10.1007/s13361-017-1869-7
https://doi.org/10.1007/s13361-017-1869-7
Autor:
Lisandra E. de Castro Brás, Merry L. Lindsey, Jitka A. I. Virag, Zamaneh Kassiri, Marielle Scherrer-Crosbie
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology
Cardiovascular disease is a leading cause of death, and translational research is needed to understand better mechanisms whereby the left ventricle responds to injury. Mouse models of heart disease have provided valuable insights into mechanisms that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf012305b313f308bd0086a5e21eeb1c
http://europepmc.org/articles/PMC5966769
http://europepmc.org/articles/PMC5966769
Autor:
Omar M. Sharaf, Justin Parks, Jeffrey J. Brault, Uma M Sharma, Randall H. Renegar, Jitka A. I. Virag, Smrithi Valsaraj, P. Darrell Neufer, Brinda Sarathy, Julie L. Horton, Kelsey H. Fisher-Wellman, Maria J. Torres, Kelsey L. McLaughlin, K'Shylah S Whitehurst
Publikováno v:
Life Sci
Aims Intracardiac injection of recombinant EphrinA1-Fc immediately following coronary artery ligation in mice reduces infarct size in both reperfused and non-reperfused myocardium, but the cellular alterations behind this phenomenon remain unknown. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288bae609a513e2dae101bb1ec06d0af
https://doi.org/10.1016/j.lfs.2019.117053
https://doi.org/10.1016/j.lfs.2019.117053
Autor:
Jitka A. I. Virag, Julie L. Horton
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1449 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1449 (2019)
Myocardial tissue damage that occurs during an ischemic event leads to a spiraling deterioration of cardiac muscle structural and functional integrity. Reperfusion is the only known efficacious strategy and is the most commonly used treatment to redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0744f1ccbeabc8851c2146f9d869658d
https://doi.org/10.3390/ijms20061449
https://doi.org/10.3390/ijms20061449