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DOP03 The use and efficacy of biological therapies 2010–2020 for Inflammatory Bowel Disease in a Danish tertiary centre

Autor: M D Wewer, L Arp, S Melek, F Oluf Krautwald, I Vind, G Pedersen, A M Nielsen, M Kiszka-Kanowitz, T Boysen, K Theede, I Nordgaard-Lassen, F Bendtsen, J Burisch

Publikováno v: Journal of Crohn's and Colitis. 16:i053-i054

Background Direct health care costs have shifted towards drug-related expenditures in patients with inflammatory bowel disease (IBD). Frequently, patients will have to switch to a second- or third-line biological therapy due to no response or loss of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a6e42ef6a2920eef838bb8b904dc7f3
https://doi.org/10.1093/ecco-jcc/jjab232.042

Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease

Autor: Elaine R. Nimmo, Jack Satsangi, Colin Veal, Christopher G. Mathew, I. Vind, Peder Fode, Pia S. Munkholm, Edward J. Hollox, Natalie J. Prescott, John C. Mansfield, Paal Skyt Andersen, Shamik Polley

Publikováno v: Polley, S, Prescott, N, Nimmo, E, Veal, C, Vind, I, Munkholm, P, Fode, P, Mansfield, J, Skyt Andersen, P, Satsangi, J, G Mathew, C & Hollox, E J 2016, ' Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease ', European journal of human genetics : EJHG . https://doi.org/10.1038/ejhg.2015.280
Polley, S, Prescott, N, Nimmo, E, Veal, C, Vind, I, Munkholm, P, Fode, P, Mansfield, J, Skyt Andersen, P, Satsangi, J, Matthew, C G & Hollox, E J 2016, ' Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease ', European Journal of Human Genetics . https://doi.org/10.1038/ejhg.2015.280
European Journal of Human Genetics

Previous work has shown that the gene DMBT1, which encodes a large secreted epithelial glycoprotein known as salivary agglutinin, gp340, hensin or muclin, is an innate immune defence protein that binds bacteria. A deletion variant of DMBT1 has been p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1cd17bf71a1d8099ae198def90afc0
https://kclpure.kcl.ac.uk/ws/files/46527839/ejhg2015280a.pdf

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