Výsledky vyhledávání - "I. V. Zhigal'tsev"

Effect of long-term parenteral administration of empty andl-Dopa-loaded liposomes on the turnover of dopamine and its metabolites in the striatum of mice with experimental Parkinson’s syndrome

Autor: V. V. Yurasov, E. V. Nikushkin, V. G. Kucheryanu, I. V. Zhigal’tsev, Kaplun Ap, V. S. Kudrin, V. I. Shvets, Yu. G. Sandalov

Publikováno v: Bulletin of Experimental Biology and Medicine. 123:126-129

It is found that the dose ofl-Dopa required for correction of dopamine metabolism in experimental Parkinson’s syndrome in C57B1/6 mice can be reduced 10-fold when the preparation is incorporated into small unilamellar liposomes (60 nm) composed fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a82ea53f26a7b74c27f028e3bf929a7
https://doi.org/10.1007/bf02766431

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Effect of liposomall-Dopa on the Parkinson’s syndrome in mice

Autor: V. V. Yurasov, G. N. Kryzhanovskii, V. P. Kaplun, V. I. Shvets, E. V. Nikushkin, I. V. Zhigal’tsev, V. G. Kucheryanu

Publikováno v: Bulletin of Experimental Biology and Medicine. 123:24-27

The effects of freel-Dopa andl-Dopa enclosed in small monolamellar liposomes consisting of egg phosphatidylcholine and cholesterol (molar ratio 7:3) on the severity of Parkinson’s syndrome are studied. The syndrome is modeled in C57B1/6 mice by rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ed6c6fb114dc302e7680e406eef0a76
https://doi.org/10.1007/bf02764369

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Liposomes containing dopamine entrapped in response to transmembrane ammonium sulfate gradient as carrier system for dopamine delivery into the brain of parkinsonian mice

Autor: A. P. Kaplun, V. I. Shvets, S. N. Kolomeichuk, I. V. Zhigal’tsev, V. V. Yurasov, G. N. Kryzhanovsky, V. G. Kucheryanu

Publikováno v: Journal of liposome research. 11(1)

The active loading of liposomes with dopamine in response to an ammonium sulfate gradient was studied. This method can be regarded as a mean to more efficiently improve the liposomal dopamine/lipids ratio in comparison to conventional methods of lipo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d796cd735a362ac32c1a737b0f9dec1
https://pubmed.ncbi.nlm.nih.gov/19530919

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Effects of acidic fibroblast growth factor on the development of experimental parkinsonism and striatal level of dopamine and its metabolites in mice of different ages

Autor: I. V. Zhigal’tsev, V. V. Yurasov, E. V. Nikushkin, V. S. Kudrin, V. G. Kucheryanu, G. N. Kryzhanovskii

Publikováno v: Bulletin of Experimental Biology and Medicine. 127:454-456

Intranasal administration of acidic fibroblast growth factor suppressed the development of oligokinesia and muscular rigidity and elevated the content of dopamine and its metabolites (dihydroxyphenylacetic acid and homovanillic acid) in the striatum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9233710dfa33d36e681677abfe494c2c
https://doi.org/10.1007/bf02434936

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[Preparation and certain properties of the liposomal substance 2,4-di(1-methyl-3-hydroxybutyl)deuteroporphyrin-IX]

Autor: A V, Reshetnikov, I V, Zhigal'tsev, S N, Kolomeĭchuk, A P, Kaplun, V I, Shvets, O S, Zhukova, A V, Karmenian, A V, Ivanov, G V, Ponomarev

Publikováno v: Bioorganicheskaia khimiia. 25(10)

A liposome preparation of a porphyrin photosensitizer for photodynamic therapy of tumors (PDT) was obtained. The in vitro efficiency of the photosensitizer was enhanced 2.5-fold through the liposome formulation. The composition and some properties of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::22b1e3355236148afa9b6a1082871e15
https://pubmed.ncbi.nlm.nih.gov/10645482

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[Concentrating dopamine in liposomes using transmembrane gradient of ammonium sulfate]

Autor: I V, Zhigal'tsev, S N, Kolomeĭchuk, A P, Kaplun, V G, Kucherianu, V V, Iurasov, V I, Shvets

Publikováno v: Bioorganicheskaia khimiia. 25(5)

The active loading of liposomes from egg phosphatidylcholine and cholesterol with dopamine using an ammonium sulfate gradient was studied. Our conditions allowed the enrichment of the monolamellar liposomes with 90% dopamine added to the medium and,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cb6f79224f9d940359ff209e6490d1e
https://pubmed.ncbi.nlm.nih.gov/10495896

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Effects of L-Dopa-carrying liposomes on striatal concentration of dopamine and its metabolites and phospholipid metabolism in experimental Parkinson's syndrome

Autor: V. I. Shvets, V. V. Yurasov, Yu. G. Sandalov, V. S. Kudrin, Kaplun Ap, I. V. Zhigal’tsev, V. G. Kucheryanu, G. N. Kryzhanovskii, G. N. Podgornyi, E. V. Nikushkin

Publikováno v: Scopus-Elsevier

Intraperitoneal injection of extremely low doses ofl-Dopa-containing liposomes increases the rate of dopamine metabolism and alters the metabolism of signal phospholipids in the striatum of C57B1/6 mice with experimental parkinsonism. Liposomal lipid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47fa9ce981a7a1d50457fe39d4e04a4
http://www.scopus.com/inward/record.url?eid=2-s2.0-26944495380&partnerID=MN8TOARS

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