Zobrazeno 1 - 10
of 22
pro vyhledávání: '"I. V. Samoylenko"'
Publikováno v:
Медицинский совет, Vol 0, Iss 9, Pp 48-63 (2021)
With an increasing number of alternative effective therapies available for patients, there is an increasing need for a more accurate selection for therapy (compared to observation, for example, after radical surgical treatment), selection of the opti
Externí odkaz:
https://doaj.org/article/8ae0fa990e5041159cac2443cdd966c9
Autor:
O. E. Garanina, I. V. Samoylenko, I. L. Shlivko, I. A. Klemenova, M. S. Neznakhina, L. V. Demidov
Publikováno v:
Медицинский совет, Vol 0, Iss 9, Pp 102-120 (2020)
Introduction. Currently, numerous studies are published by authors of different countries to demonstrate the effectiveness of noninvasive methods in the diagnosis of melanoma. Methods. A systematic search was conducted independently in the databases
Externí odkaz:
https://doaj.org/article/5650539dad61464083abc8fd483680da
Autor:
I. V. Samoylenko, L. V. Demidov
Publikováno v:
Медицинский совет, Vol 0, Iss 9, Pp 80-93 (2020)
The choice of first-line therapy for metastatic skin melanoma has become quite a difficult task in the last few years: a practicing oncologist has got drugs of different classes with different mechanisms of action – immune checkpoint blockers and B
Externí odkaz:
https://doaj.org/article/d54866064dfe4b9cb23833eec44fef0d
Autor:
A. A. Vartanian, O. S. Burova, Kh. S. Vishnyakova, I. V. Samoylenko, V. A. Misyurin, E. E. Egorov, O. O. Ryabaya, M. A. Baryshnikova
Publikováno v:
Успехи молекулярной онкологии, Vol 6, Iss 4, Pp 47-57 (2019)
Background. Activating mutations in the BRAF gene leads to a constitutive activation of the MAPK signaling. The highly selective BRAFV600E inhibitor, vemurafenib, improves the overall survival of BRAF-mutant melanoma patients. However, despite the ex
Externí odkaz:
https://doaj.org/article/2c60eba51be74945a5a4cbe6c09cdbeb
Publikováno v:
Медицинская иммунология, Vol 21, Iss 1, Pp 59-68 (2019)
Inhibitory receptors CTLA-4 and PD-1 (immune checkpoints) play a key role in regulation of immune reactions. They suppress excessive immune response against pathogenic microbes and prevent autoimmune reactions. The immune checkpoints are targets of t
Externí odkaz:
https://doaj.org/article/ca1be543ea6845e3bdecf5e1eee5a835
Publikováno v:
Российский кардиологический журнал, Vol 0, Iss 12, Pp 62-67 (2017)
Aim. To evaluate the prevalence and to search for the risk factors of atrial fibrillation (AF) development in patients with implantable cardiac electronic devices (dualchamber stimulators (ECS), implantable cardioverter-defibrillators and resynchroni
Externí odkaz:
https://doaj.org/article/2b85c721a5004698b04c0885bec0d440
Publikováno v:
Медицинский совет, Vol 0, Iss 14, Pp 6-10 (2017)
Development of new effective drugs for therapy of metastatic melanoma (BRAF/MEK inhibitors, PD1/CTLA4 blockers) requires additional studies of the optimal sequence of their use. But in many cases the duration of the effect of these medicinal products
Externí odkaz:
https://doaj.org/article/3d0e676c5f174d958d792cd30271f5e4
Autor:
D. R. Naskhletashvili, V. A. Gorbunova, A. Kh. Bekyashev, L. V. Demidov, G. Yu. Kharkevich, S. M. Banov, I. V. Samoylenko, K. А. Baryshnikov, K. V. Orlova, I. А. Utyashev, N. N. Petenko, I. G. Markina, E. A. Moskvina, S. V. Medvedev
Publikováno v:
Опухоли головы и шеи, Vol 6, Iss 4, Pp 30-34 (2017)
The effectiveness of traditional chemotherapy (with temozolomide, fotemustine, lomustine) alone or in combination with whole brain radiotherapy in melanoma patients with cerebral metastases does not exceed 7–10 % with no significant impact on survi
Externí odkaz:
https://doaj.org/article/b2ac3cf2f6194ffca9ad2854e4269286
Autor:
Yu. A. Khochenkova, G. Z. Chkadua, I. V. Samoylenko, T. F. Malivanova, I. N. Mikhailova, L. V. Demidov, E. V. Stepanova
Publikováno v:
Медицинская иммунология, Vol 15, Iss 6, Pp 563-570 (2014)
Abstract. Increased VEGF levels in cancer patients may be associated with decreased number of dendritic cells (DCs) and lower DC function. We investigated whether VEGF gene polymorphisms -2578C>A (rs699947) and +936C>T (rs3025039) are associated with
Externí odkaz:
https://doaj.org/article/eeb026a56774434f9e4bf5856688d7d3
Publikováno v:
Российский кардиологический журнал, Vol 0, Iss 2, Pp 79-84 (2012)
Management of chronic heart failure (CHF) remains one of the most important problems in modern cardiology. Despite the recent pharmacotherapy successes, substantial numbers of CHF patients remain resistant to pharmaceutical treatment. Over the last d
Externí odkaz:
https://doaj.org/article/2c0ad2568db041b79248ecdcd0380ce7