Zobrazeno 1 - 10
of 20
pro vyhledávání: '"I. V. Gravel"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 103-116 (2024)
Introduction. Determination of pesticide residues presence in herbal plants and preparations based on them is an important step in confirming safety at the stage of the quality control of herbal plants. The usage of organophosphate pesticides (OPs) f
Externí odkaz:
https://doaj.org/article/c8833f7669214722a336210becea6cc2
Autor:
E. O. Bakhrushina, I. V. Gravel, O. S. Filippova, V. N. Tychinin, A. A. Popova, O. B. Dobrovolsky
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 2, Pp 34-47 (2024)
Introduction. The secretome of mesenchymal stem cells (SMSC) is widely used in medicine. It is most often used due to its immune-modulating and regenerative properties in the treatment of autoimmune, immuno-mediated and other diseases due to its anti
Externí odkaz:
https://doaj.org/article/881fadf9edda46e387387f995edffb05
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 2, Pp 171-180 (2024)
INTRODUCTION. The influence of anthropogenic factors on the content of toxic elements in plants increases the need for monitoring the content of toxic elements in medicinal plant raw materials and the corresponding herbal medicinal products. In addit
Externí odkaz:
https://doaj.org/article/69d2aab0fc054455905683590cbf768c
Autor:
U. V. Ivanova, I. V. Gravel
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 1, Pp 95-109 (2024)
Introduction. Aflatoxins and ochratoxin A are secondary metabolites of microscopic mold fungi. They seriously threaten human and animal health. These toxins are carcinogenic, teratogenic, hepatotoxic, nephrotoxic substances. International Agency for
Externí odkaz:
https://doaj.org/article/b50d0b805e814fd0ac9577aa662bae02
Autor:
M. S. Galenko, I. V. Gravel
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 3, Pp 442-452 (2023)
Scientific relevance. In the context of pharmacopoeial harmonisation, the available methods for quantifying the total heavy metal content in tinctures are not sufficient to demonstrate the safety of liquid dosage forms based on herbal drugs. However,
Externí odkaz:
https://doaj.org/article/b098952d3dce416994c2f68f7754f4ec
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 2, Pp 128-133 (2023)
Herbal drugs and herbal medicinal products remain of interest to Russian researchers both in terms of the development, efficacy, and safety of medicines, and in terms of the research methodology applicable to these medicine, as well as the use of new
Externí odkaz:
https://doaj.org/article/d2e45a79273743c1b5ebd12870b95901
Autor:
I. V. Gravel, D. V. Levushkin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 2, Pp 113-123 (2023)
Introduction. Trace elements are an essential part of the human body, but about 80 % of the human population notes an imbalance in their content. Medicinal plants contain minerals in an accessible and digestible form together with biologically active
Externí odkaz:
https://doaj.org/article/ef1187abcdcc4519bf5fad8784e49ef4
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 11, Iss 3, Pp 137-151 (2022)
Introduction. Usage of organophosphate pesticides (OPPs) in agriculture, including farming of medical herbs, is a necessary measure for producing regular harvest. In order to maintain an adequate degree of herbal medicines security a variety of count
Externí odkaz:
https://doaj.org/article/755894f9107e4c80b97b5b9fd769ccb2
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 12, Iss 2, Pp 173-182 (2022)
To ensure the safety of herbal medicinal products, particularly in liquid dosage forms, it is necessary to control environmental toxins to acceptable levels. However, there is no methodology for individual elemental impurities in tinctures. The aim o
Externí odkaz:
https://doaj.org/article/49f292b67e4a425eb4f306cf0d62fe6b
Publikováno v:
Безопасность и риск фармакотерапии, Vol 9, Iss 2, Pp 61-68 (2021)
Herbal medicinal products (HMPs) are widely used in medical practice due to their availability, ease of use, and relatively safe pharmacological profile. However, medicinal plants are capable of accumulating heavy metals and arsenic which can have t
Externí odkaz:
https://doaj.org/article/ce96877d5d064103b9c500e46f6f5c3a