Zobrazeno 1 - 10 of 213 pro vyhledávání: '"I. Umezawa"'
2
Symmetric covalent linkage of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) results in novel derivatives with increased inhibitory activities against calcium/calmodulin complex
Autor: H, Yokokura, M, Osawa, T, Inoue, I, Umezawa, Y, Naito, M, Ikura, H, Hidaka
Publikováno v: Drug design and discovery. 16(3)
A useful calmodulin (CaM) antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), was invented by Hidaka et al. in 1978 (J. Pharmacol. Exp. Ther. 207, 8-15). Here, we have designed new CaM antagonists on the basis of the three-dimension
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d3c55b5ac062c679c005940c1955d61
https://pubmed.ncbi.nlm.nih.gov/10624566
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3
Patents and literature
Autor: Robert J. Linhardt, E. A. Balazs, D. J. Wedlock, G. O. Phillips, A. Leshchiner, R. S. Langer, R. J. Linhardt, C. L. Cooney, G. Fitzgerald, A. Grant, S. E. Lasker, J. C. Lormeau, J. Choay, J. Goulay, M. T. Goulay-Heir, M. A. Goulay-Heir, G. Goulay-Heir, M. Petitou, D. B. Soll, S. E. Harrison, L. L. Teng, A. G. Walton, R. V. Sparer, N. Ekwuribe, J. K. Borchardt, J. W. Bracke, K. Thacker, P. Brocklehurst, A. S. Ferguson, L. K. Gordon, H. Hayes, S. Inoue, H. Yamamoto, A. M. Nonomura, R. Pappo, J. M. Schweid, A. H. Cohee, A. F. Dec, L. K. Shay, S. E. Reiter, L. Turrisi, I. Umezawa, K. Komiyama, D. Williams, D. M. Munnecke, R. T. Zahradnik, K. Arizono, M. Terasawa, M. Nobutoki, L. C. A. Bergwitz, R. G. L. Osterlund, C. Brain, B. Johnston, L. G. Brooker, T. S. Chang, L. J. Zientek, A. Viniguaz, I. Chibata, T. Tosa, S. Takamatsu, D. F. Doehnert, A. S. Hill, D. P. Gaehring, J. V. Scanlon, G. D. Hansen, K. M. E. Hellsten, R. L. Horion, R. B. Kennedy, R. S. Kohn, A. J. Kruger, J. K. Johnson, W. Y. Kuu, V. K. Larsson, J. F. Mezzino, L. Y. Chuang, J. Michnowski, Y. Miyashiro, M. Ogawa, Y. Yamazaki, S. Igarasi, K. Morimoto, S. Nochumson, M. A. Pellico, R. J. Purinton, F. Reinhardt, K. Sakata, H. Imai, A. J. Sensabaugh, D. C. Crepps, W. Y. Rice, G. W. Fearrington, J. L. Shim, Y. Shimohiro, T. Ohnishi, E. Simon, H. Stuhler, E. Krempl, D. T. Su, K. Szendrei, E. Minker, Z. Re, L. Koch, L. Wolf, E. Szijj, M. Re, M. Trop, D. C. Tunc, T. Ueda, M. Vellini, R. B. Wallace, K. Watanabe, S. Yoshikawa, S. Futami, R. H. Wunder
Publikováno v: Applied Biochemistry and Biotechnology. 12:177-197
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85e331276b6ca19c54786cc792be5bad
https://doi.org/10.1007/bf02798421
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4
Antitumor effect of 3-[3-(2-chloroethyl)-3-nitrosoureido]-3-deoxy-D-glucopyranose on murine tumors
Autor: K, Komiyama, K, Edanami, T, Kuroda, I, Umezawa
Publikováno v: Gan. 72(1)
The antitumor activity of a new derivative of nitrosourea, 3-[3-(2-chloroethyl)-3-nitrosoureido]-3-deoxy-D-glucopyranose (CNUG), against murine tumors was studied. CNUG showed remarkable antitumor activity against leukemias L1210 and P388, Lewis lung
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6de11b3d5bc77f7e2811bb89ae5e992d
https://pubmed.ncbi.nlm.nih.gov/6456168
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5
[Potentiation of chemotherapeutic activity by a Chinese herb medicine juzen-taiho-toh]
Autor: K, Komiyama, Y, Hirokawa, Y, Zhibo, I, Umezawa, T, Hata
Publikováno v: Gan to kagaku ryoho. Cancerchemotherapy. 15(5)
Antitumor activity of Juzen-Taiho-Toh (JTX) and combination effect of JTX with antitumor agents were studied using murine tumors. In order to determine the antitumor activity of JTX, mice inoculated ip with IMC carcinoma (1 X 10(6) cells/CDF1 mouse),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eeecd9758a8f5049624c12614773ca0c
https://pubmed.ncbi.nlm.nih.gov/3130806
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7
Immunological studies on the antitumor effect of sporamycin
Autor: I, Umezawa, K, Komiyama, Y, Kawakubo, N, Koyanagi, H, Arai, Y, Nishiyama
Publikováno v: Gan. 72(4)
The role of immunological effects in the antitumor activity of sporamycin activity of sporamycin was studied mainly using the mouse syngeneic tumor, Meth-A. Sporamycin inhibited the growth of the Meth-A tumor and Balb/c mice, and 12 out of 19 mice we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12c5e488ae8a199d062ec93ac518c10a
https://pubmed.ncbi.nlm.nih.gov/6975730
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8
Short Wavelength AlGaInP Laser Diode Research At Sony
Autor: T. Mamine, K. Honda, N. Yamamoto, K. Kaneko, H. Satoh, I. Umezawa, M. Ikeda, C. Kojima
Publikováno v: SPIE Proceedings.
Recent research and development work on AlGaInP visible laser diodes by SONY are reviewed. Performance and reliability of a gain-guided 670 nm laser with a tapered geometry are described. Efforts for achieving shorter wavelengths around 650 nm with u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04bba2199d445eca48fa2941ae0736b6
https://doi.org/10.1117/12.951868
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10
[Biological activities of a new antitumor antibiotics]
Autor: I, Umezawa
Publikováno v: Gan to kagaku ryoho. Cancerchemotherapy. 11(12 Pt 2)
The antitumor antibiotic sporamycin is composed of polypeptide and non-chromophore subunits and shows remarkable antitumor activity against various animal tumors. The mechanism of action of this compound involves host-mediated antitumor activity as w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::195d35c025260f4db1e5d383784e7029
https://pubmed.ncbi.nlm.nih.gov/6439122
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