Zobrazeno 1 - 10
of 5 681
pro vyhledávání: '"I. Suzuki"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 2, Pp 267-278 (2022)
Construction of in vitro functional assay systems using human-induced pluripotent stem cells (iPSCs) as indicators for evaluating seizure liability of compounds has been anticipated. Imbalance of excitation/inhibition (E/I) inputs triggers seizure; h
Externí odkaz:
https://doaj.org/article/44bb1023f7044494ae652535ac8390f4
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract In vitro microelectrode array (MEA) assessment using human induced pluripotent stem cell (iPSC)-derived neurons holds promise as a method of seizure and toxicity evaluation. However, there are still issues surrounding the analysis methods us
Externí odkaz:
https://doaj.org/article/b58e9a85f46e4b3caaa29acc28e1f91e
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101148- (2021)
Brain organoids with three-dimensional structure and tissue-like function are highly demanded for brain disease research and drug evaluation. However, to our knowledge, methods for measuring and analyzing brain organoid function have not been develop
Externí odkaz:
https://doaj.org/article/783078b7e71c4055816e2558d81a313e
Publikováno v:
Biochemistry and Biophysics Reports, Vol 17, Iss , Pp 122-126 (2019)
The natural antioxidant Thymoquinone (TQ) is the most abundant ingredient in the curative plant Nigella sativa seed's oil. An extensive number of studies have revealed that TQ is the most active and most responsible component for the plant's pharmaco
Externí odkaz:
https://doaj.org/article/d8b846a38c4c4e5aaff152bb3e4c91a4
Autor:
M. Yashi, M. Yokoyama, H. Fuchizawa, N. Okubo, R. Kurashina, K. Takei, I. Suzuki, K. Sakamoto, A. Nukui, Y. Fukabori, T. Kamai
Publikováno v:
European Urology Open Science, Vol 19, Iss , Pp e895- (2020)
Externí odkaz:
https://doaj.org/article/5e72cd62c7874a5297c7b04a0f0b3127
Publikováno v:
Revista Argentina de Radiología, Vol 80, Iss 3, Pp 162-169 (2016)
Objetivo: Describir los resultados de la embolización portal hepática (EPH) preoperatoria con lipiodol y gelatina absorbible para generar hipertrofia hepática y permitir la hepatectomía derecha en pacientes con tumores hepáticos e hígado remane
Externí odkaz:
https://doaj.org/article/ca7d974fccd0436fb093d1387f0df1cb
Publikováno v:
Biogeosciences, Vol 13, Iss 9, Pp 2743-2755 (2016)
Strains of the coccolithophore Emiliania huxleyi (Haptophyta) collected from the subarctic North Pacific and Arctic oceans in 2010 were established as clone cultures and have been maintained in the laboratory at 15 °C and 32 ‰ salinity. To study t
Externí odkaz:
https://doaj.org/article/305ff05d8a734d0aa4ec23f16f7c1226
Autor:
Miho M. Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, Tatsunori Nishimura, Fumiharu Ohka, Ryuta Saito, Shinya Sato, Junya Kobayashi, Ryoji Yao, Kanjiro Miyata, Kazunori Kataoka, Hiroshi I. Suzuki, Yutaka Kondo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Oncogene-induced DNA replication stress (RS) and consequent pathogenic R-loop formation are known to impede S phase progression. Nonetheless, cancer cells continuously proliferate under such high-stressed conditions through incompletely unde
Externí odkaz:
https://doaj.org/article/3a39adce796d43a99a5582287d10e0b2
Autor:
Hiroki Kitai, Noritoshi Kato, Koichi Ogami, Shintaro Komatsu, Yu Watanabe, Seiko Yoshino, Eri Koshi, Shoma Tsubota, Yoshio Funahashi, Takahiro Maeda, Kazuhiro Furuhashi, Takuji Ishimoto, Tomoki Kosugi, Shoichi Maruyama, Kenji Kadomatsu, Hiroshi I. Suzuki
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Combinatorial gene regulation by multiple microRNAs (miRNAs) is widespread and closely spaced target sites often act cooperatively to achieve stronger repression (“neighborhood” miRNA cotargeting). While miRNA cotarget sites a
Externí odkaz:
https://doaj.org/article/814489ea1fa84422a7415f8368b0e8b0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3536 (2023)
Cardiovascular complications are seen among human immunodeficiency virus (HIV)-positive individuals, who now survive longer due to successful antiretroviral therapies. Pulmonary arterial hypertension (PAH) is a fatal disease characterized by increase
Externí odkaz:
https://doaj.org/article/99d12fd66e154174b57634305915e44a