Oral anti-CD3 immunotherapy for HCV-nonresponders is safe, promotes regulatory T cells and decreases viral load and liver enzyme levels: results of a phase-2a placebo-controlled trial

Autor: Dorota Kozielewicz, N. Lisovoder, R. Ellis, S. Samira, I. Shalit, Yaron Ilan, Waldemar Halota, Dorota Dybowska, P. Ferenci

Publikováno v: Journal of Viral Hepatitis. 22:651-657

UNLABELLED Orally administered anti-CD3 antibodies are biologically active in the gut through induction of regulatory T cells, exert an immune-modulatory effect, and alleviate insulin resistance and liver damage in patients with NASH. AIMS To determi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f2caec0de813496a7bebf627edc6cb
https://doi.org/10.1111/jvh.12369

Moxifloxacin enhances antiproliferative and apoptotic effects of etoposide but inhibits its proinflammatory effects in THP-1 and Jurkat cells

Autor: Esther Priel, Debby Reuveni, Drora Halperin, Avital Levitov, Ina Fabian, I Shalit

Publikováno v: British Journal of Cancer

Etoposide (VP-16) is a topoisomerase II (topo II) inhibitor chemotherapeutic agent. Studies indicate that VP-16 enhances proinflammatory cytokines secretion from tumour cells, including IL-8, a chemokine associated with proangiogenic effects. Fluoroq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af7b59ec2cef934e55901991e166194
https://doi.org/10.1038/sj.bjc.6603355

Abstract

Autor: J. W. Bass, J. A. Rooney, K. Hadley, T. T. Brown, M. Holmberg, J. R. Claybaugh, B. C. Freitas, E. Farnetti, Y. Golan, J. Ridder, U. Fabio, L. Serra, G. Delacour, C. Garrido, R. R. Wittler, I. Shalit, P. Terenziani, H. J. Boulouis, R. Heller, R. Regnery, G. Friman, R. Berner, Russell L. Regnery, M. Sanchez, S. McGill, D. Watts, L. Cooper, L. N. Slater, C. Lyons, Y. Kletter, S. Tye, B. Richter, L. Bonazzi, A. Sander, F. Dutly, M. Maurin, M. Giladi, D. A. Person, R. Zbinden, E. Hjelm, R. Orni-Wasserlauf, M. E. Weisse, F. Chen, Arthur Reingold, A. D. Freitas, B. Casali, J. G. Olson, Jane E. Koehler, C. E. Atkins, L. Wesslen, L. Laughlin, L. Benoit, Didier Raoult, M. Ephros, G. J. Ridder, Edward B. Breitschwerdt, Jordan W. Tappero, H. Gonzales, A. Hill, C. Ponce, N. Cimolai, D. Bermond, S. Gordon, B. Avidor, M. Punder, J. M. Vincent, A. Gonzalo, Y. Piemont, J. Chamberlin, D. S. Chan, C. Carillo, A. Tuzzi, A. Fabio, S. Abulafia, Bruno B Chomel, James G. Olson, S. Romero, M. Ruess, M. Altwegg, K. A. Dubois, T. Ness, M. Brandis, B. B. Chomel

Publikováno v: Journal of Microbiological Methods. 37:267-295

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::920efcfe9717eef1e3dbf80e4e3787d3
https://doi.org/10.1016/s0167-7012(99)00073-1

Distribution of fluconazole-resistant Candida bloodstream isolates among hospitals and inpatient services in Israel

Autor: R, Ben-Ami, G, Rahav, H, Elinav, I, Kassis, I, Shalit, T, Gottesman, O, Megged, M, Weinberger, P, Ciobotaro, P, Shitrit, G, Weber, A, Paz, D, Miron, I, Oren, J, Bishara, C, Block, N, Keller, D P, Kontoyiannis, M, Giladi, Soboh, Soboh

Publikováno v: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 19(8)

The emergence of fluconazole-resistant Candida (FRC) is worrisome, but little is known about susceptibility patterns in different nosocomial settings. We prospectively analysed Candida bloodstream isolates in 18 medical centres in Israel (six tertiar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae15e83e16797d4e85320bc4184eec0
https://pubmed.ncbi.nlm.nih.gov/23005038

[Should one turn over discoveries in medical science to a financial product?]

Autor: I, Shalit

Publikováno v: Harefuah. 148(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73b7bdb9e599f9b0b936b6b4300c1472
https://pubmed.ncbi.nlm.nih.gov/19320395