Zobrazeno 1 - 10
of 151
pro vyhledávání: '"I. Saenz de Tejada"'
Publikováno v:
International Journal of Impotence Research. 15:90-93
Selective serotonin reuptake inhibitors (SSRIs) are associated with a high incidence of impotence. Paroxetine is an extensively used SSRI that has been shown to impair erectile function in patients, to induce erectile dysfunction and to inhibit nitri
Autor:
E. Lledó, Argentina Fernández, Ignacio Moncada, Javier Angulo, P Cuevas, E Bischoff, U Niewöhner, Antonio Allona, H G Körschen, E Pages, I. Saenz de Tejada, H Haning
Publikováno v:
International Journal of Impotence Research. 13:282-290
We investigated the potency and the selectivity profile of vardenafil on phosphodiesterase (PDEs) enzymes, its ability to modify cGMP metabolism and cause relaxation of penile smooth muscle and its effect on erections in vivo under conditions of exog
Publikováno v:
International Journal of Impotence Research. 12:S20-S25
The neurotransmitters and vasoactive substances regulating tone in the smooth muscle of the penile arteries/arterioles and the trabeculae of the corpora cavernosa are critical mediators of the state of penile erection. Contemporary research reveals a
Autor:
Irwin Goldstein, T.Y. Ahn, Pedro Cuevas, Victoria Sanchez Martinez, I. Saenz de Tejada, D. Gomez-Coronado
Publikováno v:
International Journal of Impotence Research. 11:9-14
We have investigated the effect of oxidatively-modified low density lipoproteins (ox-LDL) on the contractility of rabbit trabecular smooth muscle. Low density lipoproteins (LDL) were isolated from fresh human plasma pooled from multiple donors and ox
Autor:
Robert J. Krane, I. Saenz de Tejada, Dimitrios Hatzichristou, Robert B. Moreland, Ajay Nehra, Irwin Goldstein, Kazem M. Azadzoi, Daniel Udelson
Publikováno v:
International Journal of Impotence Research. 10:89-99
Purpose: The extent to which hemodynamic erectile responses predict penile buckling forces has not previously been analytically investigated. An engineering study was performed to compare hemodynamic data with penile buckling force values. Methods: D
Publikováno v:
ResearcherID
Neurotrophic factors have been shown to support the survival of injured neurons and promote their recovery. Here, we investigated whether acidic fibroblast growth factor (aFGF) could modify programmed cell death caused by transient forebrain ischemia
Autor:
Robert J. Krane, Dimitrios Hatzichristou, Robert B. Moreland, Ajay Nehra, Kazem M. Azadzoi, Irwin Goldstein, I. Saenz de Tejada, Daniel Udelson
Publikováno v:
International Journal of Impotence Research. 10:25-35
Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part II—Clinical implications of penile buckling
Autor:
Gorm Wagner, I Saenz de Tejada
Publikováno v:
BMJ. 316:678-682
Male erectile dysfunction—defined as “the inability to achieve or maintain an erection sufficient for sexual intercourse”—is one of the most common sexual dysfunctions in men.1 Although erectile dysfunction can be primarily psychogenic in ori
Publikováno v:
American Journal of Physiology-Cell Physiology. 271:C2045-C2052
We studied the effect of alloxan-induced diabetes on Na+ pump activity in isolated rabbit bladder strips. In addition, the effects of diabetes and the Na+ pump inhibitor ouabain on contractions induced by carbachol (CCh) and KCl were studied. In blad
Autor:
I. Saenz de Tejada
Publikováno v:
International Journal of Impotence Research. 16:S40-S42
Phosphodiesterase 5 (PDE5) inhibitors prevent the normal hydrolysis of cGMP. As the resulting cGMP accumulation facilitates penile smooth muscle relaxation, PDE5 inhibitors can partially reverse deficiencies in the nitric oxide (NO)/cGMP pathway to t