Zobrazeno 1 - 5
of 5
pro vyhledávání: '"I. S. Yuen"'
Publikováno v:
Toxicology Letters. 88:249-253
Long-term inhalation exposures to high dust burdens can produce tumors or proliferative keratin cysts in the lungs of exposed rats. We hypothesized that dust burdens which overwhelm lung clearance mechanisms are associated with sustained cellular pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38eae7f50c79b0a5f778685819ce73c3
https://doi.org/10.1016/0378-4274(96)82678-6
https://doi.org/10.1016/0378-4274(96)82678-6
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 15:268-274
The time course of neutrophil recruitment into the lung, neutrophilic chemotactic activity, and the gene expression of neutrophilic chemokines by lavaged cells was determined after intratracheal instillation of various particles. Low-toxicity, low-so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84abc5f9d915734e2fecc5b04119dfb5
https://doi.org/10.1165/ajrcmb.15.2.8703484
https://doi.org/10.1165/ajrcmb.15.2.8703484
Autor:
Mark A. Hartsky, John F. Hansen, Suzanne I. Snajdr, I. S. Yuen, David B. Warheit, David P. Kelly
Publikováno v:
Toxicology and applied pharmacology. 145(1)
This study was carried out to assess the time course of pulmonary clearance impairment and persistence of inflammation following high-dose inhalation exposures to titanium dioxide (TiO2) or carbonyl iron (CI) particles. Male rats were exposed to air,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40c6c49ed43937f76eb6aaec00ceaa3
https://pubmed.ncbi.nlm.nih.gov/9221819
https://pubmed.ncbi.nlm.nih.gov/9221819
Publikováno v:
The Annals of Occupational Hygiene.
Inhalation of silica particles produces a chronic pulmonary inflammation response and the development of lung fibrosis and tumors in exposed rats. A variety of cytokines have been implicated in the recruitment of neutrophils into alveolar regions, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e49ed97d0fd443993656166b9760127
https://doi.org/10.1093/annhyg/41.inhaled_particles_viii.548
https://doi.org/10.1093/annhyg/41.inhaled_particles_viii.548
Publikováno v:
Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres ISBN: 9783642790430
In vitro toxicity assays have been proposed as substitutes for acute in vivo studies during the early phases of inhalation toxicology testing. Short-term toxicity tests are needed to screen materials. Test systems generally are comprised of cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7cfac137a7e72860973b07043e9a050
https://doi.org/10.1007/978-3-642-79041-6_33
https://doi.org/10.1007/978-3-642-79041-6_33
