Zobrazeno 1 - 10
of 48
pro vyhledávání: '"I. S. Trowbridge"'
Autor:
I. S. Trowbridge, Å. Öst, P. Reizenstein, Robert Hast, B. Christensson, Peter Biberfeld, B. Lagerlöf, R B Andreasen
Publikováno v:
Scandinavian Journal of Haematology. 34:293-302
Blood cells from 46 patients with acute myeloid leukaemia were studied for expression of various surface markers, defined by a panel of 12 monoclonal antibodies and the expression of Fc gamma receptors. Corresponding studies were done on normal bone
Autor:
Michael G. Rosenfeld, James F. Collawn, M Komuro, C P Chang, Cheri S. Lazar, John A. Tainer, Marilyn G. Farquhar, B J Walsh, I. S. Trowbridge, Leslie A. Kuhn
Publikováno v:
Journal of Biological Chemistry. 268:19312-19320
Ligand-induced internalization of epidermal growth factor (EGF) receptors via a high affinity saturable pathway requires sequences located in the carboxyl terminus distal to the tyrosine kinase domain. Three regions were found to contain endocytic mo
Publikováno v:
The Journal of Immunology. 148:19-28
A mAb (I/24) has been generated that is specific for a determinant on mouse CD45 molecules. Reactivity of this mAb with a panel of CD45 transfected cell lines demonstrated that the determinant recognized is dependent upon expression of one or more CD
Autor:
I S Trowbridge, D A Shackelford
Publikováno v:
Cell Regulation. 2:73-85
Interleukin-2 (IL-2) stimulates the rapid phosphorylation on tyrosine of several specific cellular proteins. However, the high-affinity human IL-2 receptor, composed of an alpha (p55) and beta (p70/75) subunit, does not contain a cytoplasmic tyrosine
Publikováno v:
Molecular and Cellular Biology. 10:2606-2618
A 180-kilodalton (kDa) protein (p180) was identified among the antigens for a panel of monoclonal antibodies raised against human fibroblast cell surface proteins. Binding studies with 125I-Fab' fragments of an anti-p180 monoclonal antibody demonstra
Publikováno v:
The Journal of biological chemistry. 270(8)
The beta-amyloid precursor protein (APP) is proteolytically processed to generate beta-amyloid protein, the principal protein component of neuropathological lesions characteristic of Alzheimer's disease. To investigate potential sorting signals in th
Autor:
G, Odorizzi, I S, Trowbridge
Publikováno v:
Methods in cell biology.
Publikováno v:
The Journal of biological chemistry. 268(29)
By functional analysis of mutant human transferrin receptors (TR) expressed in chicken embryo fibroblasts, we previously identified a tetrapeptide sequence, Y20TRF23, within the 61-residue cytoplasmic tail as the signal for high-efficiency endocytosi
Publikováno v:
Journal of neurochemistry. 60(1)
Uptake of 59Fe from blood into brains of anaesthetized rats and mice has been studied by intravenous infusion of [59Fe]ferrous ascorbate or of 59Fe-transferrin, the results not being significantly different. Uptakes in the rat were linear with time,
Publikováno v:
The Journal of biological chemistry. 267(12)
The cytoplasmic domain of murine CD45 has been expressed using an in vitro transcription/translation system. The recombinant protein was isolated by immunoprecipitation with a specific rabbit antiserum and was shown to have protein tyrosine phosphata