Zobrazeno 1 - 10
of 104
pro vyhledávání: '"I. S. Gushchin"'
Publikováno v:
Russian Journal of Allergy. 18:20-31
BACKGROUND: Many antagonists of histamine (H1) receptor, in addition to antihistamine action, suppress allergic inflammation by inhibiting the formation and secretion of proinflammatory cytokines. The new antiallergic drug benzhydrylpiperazinyl butyl
Autor:
I S Gushchin, Ekaterina N Medunitsyn
Publikováno v:
Russian Journal of Allergy. 17:93-100
Antihistamines have long been an integral part of the treatment of allergic rhinitis and urticaria. Treatment of these diseases is usually long-term, so the drugs of choice are H1-antihistamines of the second generation, which have high efficiency an
Publikováno v:
Russian Journal of Allergy. 14:30-36
Background. Clinical application of leukocyte histamine release assay (HRA) can be enhanced through the development of automated reversed-phase high-performance liquid chromatography with mass spectrometry (RP-HPLC-MS/MS) employing of whole blood (WB
Autor:
I V Danilicheva, I S Gushchin
Publikováno v:
Russian Journal of Allergy. 14:89-97
Data on pharmacokinetics and pharmacodynamics, efficacy and safety of ebastin, a review of clinical studies of therapy of allergic rhinitis, chronic idiopathic urticaria and other dermatoses are presented.
Autor:
I S Gushchin
Publikováno v:
Russian Journal of Allergy. 13:3-10
The paper is focused on structure and functions of airway epithelial barrier and allergen-mediated innate immune response of the epithelium leading to facilitation of allergy development.
Publikováno v:
Russian Journal of Allergy. 13:43-51
Background. The aim of this study was to investigate the efficacy of the allergen-specific immunotherapy (ASIT) with monomeric allergoid (sD1) obtained by succinylation of the allergenic extract from house dust mite Dermatophagoides pteronyssinus (D.
Autor:
V V Smirnov, A A Laskin, I S Gushchin, Andreev Sm, A.A. Babakhin, K K Babievsky, Musa Khaitov
Publikováno v:
Russian Journal of Allergy. 13:29-36
Background. The purpose of this study was to characterize the immunologic properties of the monomeric allergoid obtained from house dust mite Dermatophagoides pteronyssinus (D. pteronyssinus) extract. Methods. To obtain monomeric allergoid the extrac
Autor:
I P Shilovskiy, A.A. Babakhin, N N Shershakova, Musa Khaitov, O Yu Kamishnikov, I S Gushchin, A A Laskin, V M Berzhets
Publikováno v:
Russian Journal of Allergy. 12:25-33
The purpose of this study was to develop a mouse model of asthma (MMA) using house dust mite Dermatophagoides pteronyssinus (Der p) extract. Methods. BALB/c mice were i.p. immunized with different doses of Der p lyophilized extract three times in thr
Autor:
I S Gushchin
Publikováno v:
Russian Journal of Allergy. 11:7-16
The paper has given an insight of allergy as evolutionary selected reactivity for highly organized animals. This reactivity is directed to organization of allergen-specific inflammation and serves as biologically expedient, high-specific and high-sen
Autor:
I S Gushchin
Publikováno v:
Russian Journal of Allergy. 11:11-24
The burden of allergic diseases worldwide is such that it represents a serious public health problem that attracts considerable efforts to identify effective and safe therapies. Antihistamines are an important part of the therapeutic options for alle