Zobrazeno 1 - 10
of 17
pro vyhledávání: '"I. Raul Badell"'
Publikováno v:
Kidney International Reports, Vol 8, Iss 12, Pp 2529-2545 (2023)
Belatacept is the first costimulatory blockade agent clinically approved for transplant immunosuppression. Although more than 10 years of study have demonstrated that belatacept offers superior long-term renal allograft and patient survival compared
Externí odkaz:
https://doaj.org/article/c18be5862c2043f78b0c94ec30702556
Autor:
Aileen C. Johnson, MD, Geeta M. Karadkhele, MS, Neeta Shenvi, MS, Kirk A. Easley, PhD, Christian P. Larsen, MD, DPhil, I. Raul Badell, MD
Publikováno v:
Transplantation Direct, Vol 9, Iss 3, p e1449 (2023)
Background. Maintenance immunosuppression with belatacept following kidney transplantation results in improved long-term graft function as compared with calcineurin inhibitors. However, broad application of belatacept has been limited, in part relate
Externí odkaz:
https://doaj.org/article/9079cb3d5fcd4fe8998c6d02ff354f0f
Autor:
Emma S. Crichton, MD, MPH, Shan Zeng, MD, PhD, G. Michael La Muraglia, II, PhD, I. Raul Badell, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 12, p e785 (2021)
Background. Donor-specific antibodies (DSA) are a recognized cause of allograft injury, yet biomarkers that indicate their development posttransplant or guide management are not available. CXCL13 (chemokine [C-X-C motif] ligand 1) is a chemoattractan
Externí odkaz:
https://doaj.org/article/944df3f4cb9c4559bf0b7959bcd41b16
Autor:
Robert Achram, Patricia E. Zerra, Bhaveshkumar Delvadia, Louisa Thompson, I. Raul Badell, John D. Roback, H. Cliff Sullivan
Publikováno v:
Transfusion. 62(9)
Publikováno v:
Transplantation Direct, Vol 7, Iss 12, p e785 (2021)
Transplantation Direct
Transplantation Direct
Supplemental Digital Content is available in the text.
Background. Donor-specific antibodies (DSA) are a recognized cause of allograft injury, yet biomarkers that indicate their development posttransplant or guide management are not available. C
Background. Donor-specific antibodies (DSA) are a recognized cause of allograft injury, yet biomarkers that indicate their development posttransplant or guide management are not available. C
Autor:
Kirk Easley, Antonio Guasch, Stephen O. Pastan, Christian P. Larsen, Robert A. Bray, Rivka Elbein, Ashtar Chami, Howard M. Gebel, I. Raul Badell, Andrew B. Adams
Publikováno v:
Transplantation. 105(12)
Publikováno v:
Curr Transplant Rep
PURPOSE OF REVIEW: Highlight developments in T and B cell biology that are helping elucidate the mechanisms underlying CD28 pathway blockade-mediated inhibition of alloantibodies in transplantation, and discuss recent clinical observations on the imp
Autor:
Melissa A. Willman, Norma S. Kenyon, Susan A. Safley, Stephanie Duncanson, I. Raul Badell, Collin J. Weber, Dora M. Berman, Athanassios Sambanis, Robert W. Holdcraft, Lawrence S. Gazda, Camillo Ricordi, Neal N. Iwakoshi, Peter Thompson, Graham F. Barber
Publikováno v:
Xenotransplantation. 25(6)
Background Xenogeneic donors would provide an unlimited source of islets for the treatment of type 1 diabetes (T1D). The goal of this study was to assess the function of microencapsulated adult porcine islets (APIs) transplanted ip in streptozotocin
Publikováno v:
JCI insight. 3(1)
Memory T cells pose a significant problem to successful therapeutic control of unwanted immune responses during autoimmunity and transplantation, as they are differentially controlled by cosignaling receptors such as CD28 and CTLA-4. Treatment with a
Autor:
I. Raul Badell, Mandy L. Ford
Publikováno v:
Current opinion in organ transplantation. 21(1)
PURPOSE OF REVIEW T follicular helper (Tfh) cells are an increasingly relevant CD4 T cell subset responsible for the provision of help to B cells for the generation of an effective humoral immune response. Here we review recent studies that have prov