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Akademický článek

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Development of QSAR models for predicting anti-HIV-1 activity using the Monte Carlo method

Autor: Toropov, A. A., A, Toropova, P., I. Raska J. r., Benfenati, E., Gini, Giuseppina

Publikováno v: Open Chemistry, Vol 11, Iss 3, Pp 371-380 (2013)

Abstract The CORAL software (http://www.insilico.eu/coral/) has been examined as a tool for modeling anti-HIV-1 activity by quantitative structure — activity relationships (QSAR) for three different sets: (i) TIBO derivatives (n=82) (ii) anti-HIV-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787f93e214633387cfa161672846066d
http://hdl.handle.net/11311/729975

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The impact of diabetes mellitus on skeletal health: an established phenomenon with inestablished causes?

Autor: I, Raska, P, Broulík

Publikováno v: Prague medical report. 106(2)

Diabetes mellitus and osteoporosis affect a large proportion of older adults. In this context, diabetes may influence the bone in multiple pathways, some with contradictory effects. These mechanisms include changes in insulin and insulin-like growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21adaeaa6e6a27b209987190200baefc
https://pubmed.ncbi.nlm.nih.gov/16315762

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An ATP-dependent step is required for the translocation of microinjected precursor mRNA into nuclear speckles

Autor: V, Kopský, J, Vecerová, I, Melcák, A, Pliss, J, Stulík, K, Koberna, L, Tomásková, I, Raska

Publikováno v: Folia biologica. 48(2)

Nuclear speckles (speckles) represent a distinct nuclear compartment within the interchromatin space and are enriched in splicing factors. In a previous study (Melcák et al., 2001), it has been shown that the pre-spliceosomal assembly on microinject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4e98626789104d0a9b84b8131a44916
https://pubmed.ncbi.nlm.nih.gov/12002677

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Akademický článek

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The yeast Ura2 protein that catalyses the first two steps of pyrimidines biosynthesis accumulates not in the nucleus but in the cytoplasm, as shown by immunocytochemistry and Ura2-green fluorescent protein mapping

Autor: P, Benoist, P, Feau, A, Pliss, J, Vorisek, R, Antonelli, I, Raska, M, Denis-Duphil

Publikováno v: Yeast (Chichester, England). 16(14)

The Ura2 multidomain protein catalyses the first two steps of pyrimidines biosynthesis in Saccharomyces cerevisiae. It consists of a 240 kDa polypeptide which contains carbamyl phosphate synthetase and aspartate transcarbamylase domains. The Ura2 pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20aba8c48bbc9f35714d8890aba0186a
https://pubmed.ncbi.nlm.nih.gov/11015727

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The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA

Autor: W, Schul, B, Groenhout, K, Koberna, Y, Takagaki, A, Jenny, E M, Manders, I, Raska, R, van Driel, L, de Jong

Publikováno v: The EMBO journal. 15(11)

The cleavage stimulation factor (CstF), and the cleavage and polyadenylation specificity factor (CPSF) are necessary for 3'-terminal processing of polyadenylated mRNAs. To study the distribution of 3' cleavage factors in the nuclei of human T24 cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ca227089c0468cd26f647c24f5785ab
https://pubmed.ncbi.nlm.nih.gov/8654386

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Experimental thyroiditis in guinea pigs and rabbits. Immunization with thyroglobulin and bovine thyroid gland suspension

Autor: J, Velický, M, Titlbach, R, Dvorák, R, Lustig, I, Raska, H, Lhotová, M, Mára, Z, Likovský

Publikováno v: Functional and developmental morphology. 3(4)

Morphological changes in the thyroid glands of the guinea pigs with autoimmune thyroiditis (EAT) experimentally induced by thyroglobulin (TGL) or immunization by the suspension of thyroid gland cells with CFA manifested mainly by atrophy and alterati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1003cf029d0c4bcb1d408709003c3204
https://pubmed.ncbi.nlm.nih.gov/7949404

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Compartmentalization of the cell nucleus: case of the nucleolus

Autor: M. Dundr, I. Raska

Publikováno v: Chromosomes Today ISBN: 9789401046602

The nucleolus is the most prominent nuclear organelle. Only one major function is ascribed to the nucleolus: here ribosomal RNA (rRNA) is transcribed, processed and assembled into preribosomal particles (Reeder, 1990 Warner,1990). The growing eukaryo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7811be0645a356a069feb517eed1008
https://doi.org/10.1007/978-94-011-1510-0_8

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