Zobrazeno 1 - 10
of 118
pro vyhledávání: '"I. Pizer"'
Publikováno v:
Journal of Virology. 77:6979-6987
To determine the type of cell(s) that contain latent varicella-zoster virus (VZV) DNA, we prepared pure populations of neurons and satellite cells from trigeminal ganglia of 18 humans who had previously had a VZV infection. VZV DNA was present in 34
Autor:
Gary H. Cohen, Sarah M. Richart, Roselyn J. Eisenberg, Scott A. Simpson, Lewis I. Pizer, J. Charles Whitbeck, Claude Krummenacher, Christine L. Wilcox
Publikováno v:
Journal of Virology. 77:3307-3311
Primary cultures of rat and mouse sensory neurons were used to study the entry of herpes simplex virus type 1 (HSV-1). Soluble, truncated nectin-1 but not HveA prevented viral entry. Antibodies against nectin-1 also blocked infection of rat neurons.
Publikováno v:
Journal of Virological Methods. 104:21-32
A method is described for fractionating human trigeminal ganglia into highly purified populations of neurons and satellite cells in order to study alpha-herpesvirus latency. The method was validated by microscopy of the separated populations and by t
Publikováno v:
Scopus-Elsevier
Activation of the early and late genes of herpes simplex virus type 1 during infection in tissue culture requires functional immediate-early regulatory protein ICP4. ICP4 is a specific DNA-binding protein which recognizes a variety of DNA sequences,
Publikováno v:
Nucleic Acids Research. 19:477-483
The herpes simplex virus type 1 regulatory protein ICP4 is a sequence specific DNA binding protein which associates with a number of different sites, some of which include the consensus ATCGTCnnnnYCGRC. In order to investigate the involvement in DNA
Autor:
Guang-Yun Cai, Scott A. Simpson, Kara R. Mizokami, Bruce W. Banfield, Myron J. Levin, Lewis I. Pizer, Renée L. Finnen
Productive infection of varicella-zoster virus (VZV) in vitro is restricted almost exclusively to cells derived from humans and other primates. We demonstrate that the restriction of productive VZV infection in CHO-K1 cells occurs downstream of virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5c0a41f8fbf5b8e62e11a9baab28d0
https://europepmc.org/articles/PMC1641800/
https://europepmc.org/articles/PMC1641800/
Autor:
Myron J. Levin, Lewis I. Pizer, Elizabeth J. Hager, Curt R. Freed, Gary H. Cohen, Christine L. Wilcox, J. Charles Whitbeck, Claude Krummenacher, Roselyn J. Eisenberg, Michael D. Manchak, Scott A. Simpson
Publikováno v:
Journal of neurovirology. 11(2)
Immunocytochemistry detects nectin-1/HveC, nectin-2/HveB, and HVEM/HveA on the surface of sensory neurons and fibroblasts grown as primary cultures from human dorsal root ganglia. Viral entry into these cultured cells was assayed by infection with a
Publikováno v:
The EMBO journal. 16(19)
High mobility group protein 1 (HMG1) is an abundant non-histone chromosomal protein which plays a role in several nuclear events involving DNA. Here we demonstrate that HMG1 physically interacts with the human adeno-associated virus (AAV) Rep protein
Publikováno v:
Virology. 187(1)
Herpes simplex virus type 1 (HSV-1) mutant viruses lacking functional viral thymidine kinase activity are reported to be incapable of replication in neurons. To investigate the role of viral thymidine kinase (TK) activity in the HSV-1 infection of th
Publikováno v:
Virology. 183(1)
The transcriptional studies reported in this paper indicate that the latency-associated transcript (LAT) is present in neuronal cultures during the latent infection with herpes simplex virus type 1 (HSV-1). During the latent infection glycoprotein D