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Experimental Comparison of Knife-Edge and Multi-Parallel Slit Collimators for Prompt Gamma Imaging of Proton Pencil Beams

Autor: Carlo Fiorini, Frauke Roellinghoff, Etienne Testa, I. Perali, Guillaume Janssens, Nicolas Freud, Julien Smeets, Damien Prieels, Andrea Celani

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Frontiers, 2016, 6, pp.156. ⟨10.3389/fonc.2016.00156⟩

International audience; More and more camera concepts are being investigated to try and seize the opportunity of instantaneous range verification of proton therapy treatments offered by prompt gammas emitted along the proton tracks. Focusing on one-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f483635f5c98bc5a8967dbe74a569d18

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Detection of mixed-range proton pencil beams with a prompt gamma slit camera

Autor: M. Priegnitz, Guillaume Janssens, I. Perali, Julien Smeets, F. Vander Stappen, S. Helmbrecht, Edmond Sterpin, Fine Fiedler

Publikováno v: Physics in medicine and biology. 61(2)

With increasing availability of proton and particle therapy centers for tumor treatment, the need for in vivo range verification methods comes more into the focus. Imaging of prompt gamma rays emitted during the treatment is one of the possibilities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e14ed89be13ed2e93dcdd2e333e30b
https://pubmed.ncbi.nlm.nih.gov/26740512

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First clinical application of a prompt gamma based in vivo proton range verification system

Autor: François Vander Stappen, Christian Richter, M. Priegnitz, Damien Prieels, J. Thiele, I. Perali, Luca Bombelli, Isabell Keitz, Guntram Pausch, Carlo Fiorini, L. Hotoiu, Michael Baumann, Julien Smeets, Wolfgang Enghardt, S. Barczyk

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 118(2)

Background and purpose To improve precision of particle therapy, in vivo range verification is highly desirable. Methods based on prompt gamma rays emitted during treatment seem promising but have not yet been applied clinically. Here we report on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2651a28d800a6316353f7e10cb674108
https://pubmed.ncbi.nlm.nih.gov/26774764

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Analytical computation of prompt gamma ray emission and detection for proton range verification

Autor: Stefaan Vynckier, I. Perali, François Vander Stappen, Julien Smeets, Guillaume Janssens, Damian Prieels, Edmond Sterpin, M. Priegnitz

Publikováno v: Physics in medicine and biology. 60(12)

A prompt gamma (PG) slit camera prototype recently demonstrated that Bragg Peak position in a clinical proton scanned beam could be measured with 1-2 mm accuracy by comparing an expected PG detection profile to a measured one. The computation of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999fd0218ad3ec25af103fc1e9244ac2
https://pubmed.ncbi.nlm.nih.gov/26057053

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First clinical application of a prompt gamma based in vivo proton range verification using a knife-edge slit camera

Autor: Luca Bombelli, Christian Richter, Michael H. Baumann, Wolfgang Enghardt, M. Priegnitz, Carlo Fiorini, L. Hotoiu, I. Perali, Guntram Pausch, Julien Smeets, F. Vander Stappen, J. Thiele, D. Prieels, I. Keitz, S. Barczyk

Publikováno v: Radiotherapy and Oncology 118(2016)Suppl. 1, S89-S90
Web of Science
ICTR-PHE 2016, International Conference on Translational Research in Radio-Oncology | Physics for Health in Europe, 15.-19.02.2016, Geneva, Switzerland

To improve precision of particle therapy, in vivo range verification is highly desirable. Methods based on prompt gamma rays emitted during treatment seem promising but have not yet been applied clinically. Here we report on the worldwide first clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e2be74e70a4a1c73770cf734cf4e3e

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First acquisitions of realistic Proton Therapy treatments delivered on an anthropomorphic phantom with a prompt gamma camera

Autor: Julien Smeets, Guillaume Janssens, Luca Bombelli, L. Hotoiu, F. Vander Stappen, I. Perali, Edmond Sterpin, R. Peloso, Damien Prieels, Carlo Fiorini, Enrico Clementel

Proton Therapy treatments are affected by uncertainties on the penetration depth of the beam within the patient. For this reason, real-time range control is highly desirable to deliver safer treatments. Real-time range control can be performed by ima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a112c3607519f505eb3b19408ce4e8db
http://hdl.handle.net/11311/987525

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A compact SiPM photodetector array for SPECT applications

Autor: Carlo Fiorini, Giulia Cozzi, Paolo Busca, Claudio Piemonte, Alessandro Ferri, M. Occhipinti, Alberto Gola, A. D. Butt, I. Perali

We propose a new compact SiPM array designed and optimized for low energies (e.g. 140 keV) and multi-tracers gamma rays detection. The final purpose of the array is to populate MR compatible SPECT systems. Coupled to a 4 mm thick CsI(Tl) scintillator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8a9d5935bcc58da320f615ee672819
http://hdl.handle.net/11311/987530

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Prompt gamma imaging of proton pencil beams at clinical dose rate

Autor: I. Perali, S. Henrotin, F. Vander Stappen, Enrico Clementel, F. Roellinghoff, Andrea Celani, Carlo Fiorini, Guillaume Janssens, Luca Bombelli, Frédéric Stichelbaut, F. Camera, Julien Smeets, Damien Prieels

Publikováno v: Phys.Med.Biol.
Phys.Med.Biol., 2014, 59 (19), pp.5849-5871. ⟨10.1088/0031-9155/59/19/5849⟩
Physics in Medicine and Biology
Physics in Medicine and Biology; Vol 59

International audience; In this work, we present experimental results of a prompt gamma camera for real-time proton beam range verification. The detection system features a pixelated Cerium doped lutetium based scintillation crystal, coupled to Silic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e056853498d06e0f2758c82b6f768a2e
https://hal.archives-ouvertes.fr/hal-02066358

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