Zobrazeno 1 - 10
of 336
pro vyhledávání: '"I. Pannacciulli"'
Publikováno v:
Anticancer research. 21(2A)
Association of all-trans retinoic acid (ATRA) and amifostine (AMF) might be an alternative in treatment of myelodisplatic syndromes. In this study we undertook a preliminary in vitro research on the effects of a combination of ATRA and AMF on normal
Publikováno v:
Anticancer research. 20(1B)
It is generally agreed that chemotherapy prolongs survival and relieves symptoms more than the best supportive care in advanced colorectal cancer. Since its introduction over 35 years ago, 5-fluorouracil (5-FU) has been the only effective chemotherap
Publikováno v:
Anticancer research. 19(3A)
Haemotoxicity is usually the primary and dose-limiting side-effect of docetaxel (TXT) a semysyntetic analogue of paclitaxel which has acquired an important role in anticancer treatment. This research presents the results of an in vitro toxicity study
Publikováno v:
Anticancer research. 19(1A)
The sequence dependency of the interaction of taxol with other anticancer drugs is of clinical importance, and may be due to pharmacokinetic changes and/or to inherent differences in the sensitivity of target normal or cancer cells. This study presen
Autor:
R, Lerza, G, Castello, P, Ballarino, G S, Mela, S, Tredici, E, Arboscello, M, Mencoboni, I, Pannacciulli
Publikováno v:
Anticancer research. 18(4A)
Hydroxyurea (HU) appears to increase 3'-azido-3'-deoxythymidine (AZT) antiretroviral activity and cytotoxicity by inhibiting thymidilate synthesis. The combination of AZT and HU may therefore be of clinical usefulness. We evaluated the in vitro hemot
Publikováno v:
Anticancer research. 18(2A)
This study presents results on 2'-2'-difluoro-2'deoxycytidine's (dFdC: gemcitabine) in vitro toxicity on peripheral blood CFU-GM and BFU-E obtained from healthy volunteers. Peripheral blood mononucleated non-adherent cells were cultured according to
Autor:
M, Mencoboni, R, Lerza, G, Castello, E, Arboscello, B P, Barsotti, A, Cerruti, P, Ballarino, M, Botta, G, Bogliolo, I, Pannacciulli
Publikováno v:
Anticancer research. 17(4A)
Vinorelbine (VNB) and Ifosfamide (IFO) have recently been proposed for treatment of non small cell lung cancer (NSCLC). The two drugs separately induce response rates in excess of 20% and, when combined, of 32.56%. Cisplatin (DDP) is considered a sta
Autor:
R, Lerza, G, Castello, G S, Mela, E, Arboscello, A, Cerruti, G, Bogliolo, M, Mencoboni, P, Ballarino, I, Pannacciulli
Publikováno v:
Experimental hematology. 25(3)
In vitro growth of human normal bone marrow granulocyte-macrophage colony forming units (CFU-GMs) and erythroid burst forming units (BFU-Es) was dose-dependently inhibited by 3'-azido-3'deoxythymidine (AZT) (from 0.1 microM to 4 microM) and 2',3'-did
Publikováno v:
Recenti progressi in medicina. 87(1)
In previous researches recombinant interferon alpha (IFN-alpha) has been demonstrated to significantly control red cell mass and thrombocytemia in patients with polycythemia vera (PV). Further evaluation of drug effectiveness and of modalities of mai
Publikováno v:
Experimental hematology. 22(13)
High-dose anticancer drugs have been shown to induce an increase in serum erythropoietin (sEpo) levels not mediated by hypoxia. In this study, sEpo was assessed in seven patients who had been administered a course of 5-day leucovorin-modulated 5-fluo