Výsledky vyhledávání - "I. P. SKRASTIN'SH"

Synthesis and pharmacological activity of silicon-containing 1,4-dihydropyridines

Autor: I. P. Skrastin'sh, L. N. Khokhlova, N. P. Erchak, E. Lukevits, R. O. Vitolinya, G. Ya. Dubur, L. E. Demicheva, V. V. Kastron

Publikováno v: Pharmaceutical Chemistry Journal. 26:775-778

Highly active cardiovascular preparations are to be found among the 4-aryl derivatives of 1,4-dihydropyridine [i, 3, 5] and 4-furyl-l,4-dihydropyridines exhibiting hypotensive and coronary dilatation activity have been synthesized [2, 6]. There are a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfb15ff2fbd7f8edf41db97c76c0dcd8
https://doi.org/10.1007/bf00770634

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Some substitution and heterocyclization reactions based on 1,4-dihydropyridines

Autor: G. Ya. Dubur, I. P. Skrastin'sh

Publikováno v: Chemistry of Heterocyclic Compounds. 28:648-657

Data on the bromination, chlorination, and bromolactonization of 4-aryl-1,4-dihydropyridines are correlated. The reactions of the products of bromination of 4-aryl-1,4-dihydropyridines with various nucleophilic agents (amines and iodide, azide, and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a95e2e55920e5e3e587917f9018f749
https://doi.org/10.1007/bf00529335

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Bromination of 4-aryl-3,5-dialkoxycarbonyl-2,6-dimethyl-1,4-dihydropyridines

Autor: I. P. Skrastin'sh, R. M. Zolotoyabko, A. é. Sausin'sh, V. V. Kastron, G. Ya. Dubur, B. S. Chekavichus

Publikováno v: Chemistry of Heterocyclic Compounds. 27:989-994

4-Aryl-3,5-dialkoxycarbonyl-2,6-dimethyl-1,4-dihydropyridines are brominated by N-bromosuccinimide in methanol at room temperature at the methyl groups at positions 2 and 6 to form mono-, di-, tri-, and tetrabromo derivatives. When the N-unsubstitute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fb971ac231ecb497b7b72ec498b2daf
https://doi.org/10.1007/bf00484364

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Reactions of N-chlorosuccinimide with 4-phenyl-1,4-dihydropyridines

Autor: I. P. Skrastin'sh, E. E. Liepin'sh, V. V. Kastron, G. Ya. Dubur

Publikováno v: Chemistry of Heterocyclic Compounds. 26:421-424

The action was studied of N-chlorosuccinimide on 2,6-dimethyl-3,5-dialkoxycarbonyl-4-phenyl-1,4-dihydropyridines. 3,4,5,6-Tetrahydropyridines having various degrees of chlorination were obtained according to the ratio between the reagents.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2dac354e066875d4bbe0d23c86764ba2
https://doi.org/10.1007/bf00497214

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