Zobrazeno 1 - 10
of 100
pro vyhledávání: '"I. P. Levshina"'
Differential early effects of traumatic brain injury on spike-wave discharges in Sprague-Dawley rats
Autor:
I. G. Komoltsev, I. P. Levshina, S. O. Frankevich, A. O. Manolova, N. I. Shirobokova, Natalia V. Gulyaeva, M. R. Novikova, A. A. Volkova
Publikováno v:
Neuroscience Research. 166:42-54
Unprovoked seizures in the late period of traumatic brain injury (TBI) occur in almost 20% of humans and experimental animals, psychiatric comorbidities being common in both situations. The aim of the study was to evaluate epileptiform activity in th
Publikováno v:
Neuroscience and Behavioral Physiology. 51:209-219
The long-term sequelae of traumatic brain injury (TBI) in humans are linked with the development of convulsions and cognitive and emotional disorders and are also associated with acceleration of brain aging processes and the formation of hippocampal
Autor:
N. I. Shirobokova, I. G. Komoltsev, A. O. Manolova, S. O. Frankevich, I. P. Levshina, A. A. Volkova, Natalia V. Gulyaeva, M. R. Novikova
Publikováno v:
Neuroscience and Behavioral Physiology. 49:1071-1075
Objectives. To identify and analyze pathological activity in the acute period of craniocerebral trauma (CCT) and to seek possible morphological correlates of this activity in the cortex and hippocampus. Materials and methods. Studies were performed u
Autor:
I. P. Levshina, M. Yu. Stepanichev, A. O. Tishkina, Natalia V. Gulyaeva, M. R. Novikova, I. G. Komoltsev
Publikováno v:
Neuroscience and Behavioral Physiology. 48:785-795
The sequelae of craniocerebral trauma (CCT) were studied using a model based on severe (3–4 atm) lateral hydrodynamic percussion (liquid-percussive brain injury) in male Sprague–Dawley rats. With the aim of detecting the symptoms of anxiety state
Autor:
A. O. Manolova, A. A. Volkova, I. P. Levshina, Natalia V. Gulyaeva, M. R. Novikova, M. Yu. Stepanichev, I. G. Komoltsev
Publikováno v:
Neurochemical Journal. 12:256-261
To evaluate the consequences of traumatic brain injury (TBI), we used a model of lateral fluid percussion brain injury in freely moving male Wistar rats. The immediate response to TBI included development of motor excitation and tonic–clonic seizur
Autor:
M Yu, Stepanichev, A O, Tishkina, M R, Novikova, I P, Levshina, A K, Piskunov, N A, Lazareva, N V, Gulyaeva
Publikováno v:
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 66(5)
We studied the effect of chronic combined stress (model of experimental neurosis) on behavior of rats with different basal strategies of behavior in novelty conditions. Chronic stress resulted in decreases in the body weight and testosterone contents
Autor:
I. P. Levshina, A. O. Tishkina, M. Yu. Stepanichev, Natalia V. Gulyaeva, M. R. Novikova, I. G. Komoltsev
Publikováno v:
Neuroscience and Behavioral Physiology. 46:826-832
Dosed lateral fluid percussion was used to model craniocerebral trauma (CCT) of moderate to severe intensity in one- and two-year-old rats. Brain sections were stained with cresyl violet by the Nissl method and with an immunochemical reaction for gli
Autor:
A. O. Tishkina, I. P. Levshina, Natalia V. Gulyaeva, M. R. Novikova, Mikhail Stepanichev, Aleksey Piskunov
Publikováno v:
Metabolic Brain Disease. 31:445-454
Hippocampus is believed to be selectively vulnerable to stress. We hypothesized that this phenomenon may be mediated by relatively high vulnerability to neuroinflammation related to impairments of local glucocorticoid metabolism and signaling. We hav
Autor:
I. P. Levshina, Mikhail V. Onufriev, Olga Levchenko, Mikhail Stepanichev, Sofiya V. Freiman, N. A. Lazareva, A. O. Tishkina, Natalia V. Gulyaeva, M. R. Novikova
Publikováno v:
Acta neurobiologiae experimentalis. 76(4)
Depression is the most common form of mental disability in the world. Depressive episodes may be precipitated by severe acute stressful events or by mild chronic stressors. Studies on the mechanisms of depression require both appropriate experimental
Autor:
A. G. Moiseenok, I. P. Levshina, Natalia Pasikova, A. O. Tishkina, Natalia V. Gulyaeva, M. R. Novikova, N. A. Lazareva, M. Yu. Stepanichev
Publikováno v:
Neurochemical Journal. 7:150-158
We studied the morphological changes and expression of the astroglial and microglial markers in the sensorimotor cortex and hippocampus of rats that were subjected to chronic stress. Chronic neurotization was associated with the appearance of a large