Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy

Autor: Astrid Z. Johansen, Sif I. Novitski, Jessica X. Hjaltelin, Susann Theile, Mogens K. Boisen, Søren Brunak, Daniel H. Madsen, Dorte L. Nielsen, Inna M. Chen

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundYKL-40, also known as chitinase-3-like protein 1 (CHI3L1), is a secreted glycoprotein produced by various cell types including stromal, immune, and cancer cells. It contributes to cancer progression through tumor-promoting inflammation and

Externí odkaz: https://doaj.org/article/17af1821af72431db2979865f0c4c06f

Development of a Bi2212 Dipole Insert at Fermilab

Autor: A. V. Zlobin, I. Novitski, E. Barzi, D. Turrioni

Publikováno v: IEEE Transactions on Applied Superconductivity. 33:1-5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f445f168e3ae9ceab0bb6f02acb19862
https://doi.org/10.1109/tasc.2023.3264165

Towards 20 T Hybrid Accelerator Dipole Magnets

Autor: P. Ferracin, G. Ambrosio, D. Arbelaez, L. Brouwer, E. Barzi, L. Cooley, L. Garcia Fajardo, R. Gupta, M. Juchno, V. Kashikhin, V. Marinozzi, I. Novitski, E. Rochepault, J. Stern, A. Zlobin, N. Zucchi

Publikováno v: IEEE Transactions on Applied Superconductivity. 32:1-6

The most effective way to achieve very high collision energies in a circular particle accelerator is to maximize the field strength of the main bending dipoles. In dipole magnets using Nb-Ti superconductor the practical field limit is considered to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98d88021e0474bf74df6dcaff060efc
https://doi.org/10.1109/tasc.2022.3152715

Development of a 120-mm Aperture Nb3Sn Dipole Coil with Stress Management

Autor: I. Novitski, A. V. Zlobin, J. Coghill, E. Barzi, D. Turrioni

This paper describes a 120-mm aperture 2-layer dipole coil with stress management (SM) developed at Fermilab based on cos-theta coil geometry. A model of the coil support structure made of plastic was printed using additive manufacturing technology a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3352b30bc5aa411778ef7555eae9a994
http://arxiv.org/abs/2204.05366

Randomized Phase II Study of Nivolumab with or Without Ipilimumab Combined with Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC)

Autor: Inna M. Chen, Julia S. Johansen, Susann Theile, Jessica X. Hjaltelin, Sif I. Novitski, Søren Brunak, Jane P. Hasselby, Gro L. Willemoe, Torben Lorentzen, Kasper Madsen, Benny V. Jensen, Eva E. Wilken, Poul Geertsen, Claus Behrens, Christian Nolsoe, Kirstine L. Hermann, Inge Marie Svane, Dorte Nielsen

Publikováno v: Chen, I M, Johansen, J S, Theile, S, Hjaltelin, J X, Novitski, S I, Brunak, S, Hasselby, J P, Willemoe, G L, Lorentzen, T, Madsen, K, Jensen, B V, Wilken, E E, Geertsen, P, Behrens, C, Nolsoe, C, Hermann, K L, Svane, I M & Nielsen, D 2022, ' Randomized Phase II Study of Nivolumab with or Without Ipilimumab Combined with Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC) ', Journal of Clinical Oncology, vol. 40, no. 27, pp. 3180-3189 . https://doi.org/10.1200/JCO.21.02511

PURPOSE To evaluate the clinical benefit of nivolumab with or without ipilimumab in combination with stereotactic body radiotherapy (SBRT) in patients with refractory metastatic pancreatic cancer (mPC). METHODS Between November 2016 and December 2019

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d517399ede567a550cd80bf191cfef2
https://curis.ku.dk/portal/da/publications/randomized-phase-ii-study-of-nivolumab-with-or-without-ipilimumab-combined-with-stereotactic-body-radiotherapy-for-refractory-metastatic-pancreatic-cancer-checkpac(ddc8b5b7-4bb4-4716-9c2f-485d7189a5c7).html