Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19

Autor: M. Attur, C. M. Petrilli, Ruth Fernandez-Ruiz, S. B. Abramson, Timothy B. Niewold, Jacqueline L. Paredes, Ashira D Blazer, A. Chakravarti, E. Iturrate, T. L. Wampler Muskardin, S. Tuminello, I. Nln

Publikováno v: medRxiv
article-version (status) pre
article-version (number) 1
Translational Research

Type I interferon (IFN) is critical in our defense against viral infections. Increased type I IFN pathway activation is a genetic risk factor for systemic lupus erythematosus (SLE), and a number of common risk alleles contribute to the high IFN trait

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49b16c59379d00d89caa7644fc970aa
https://doi.org/10.1101/2021.11.01.21265766

Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19.

Autor: Nln I; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, NY., Fernandez-Ruiz R; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, NY., Wampler Muskardin TL; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, NY., Paredes JL; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, NY., Blazer AD; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, NY., Tuminello S; Center for Human Genetics and Genomics, NYU Grossman School of Medicine, New York, NY., Attur M; Divison of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York, NY., Iturrate E; Department of Medicine, NYU Grossman School of Medicine, New York, NY., Petrilli CM; Department of Medicine, NYU Grossman School of Medicine, New York, NY., Abramson SB; Department of Medicine, NYU Grossman School of Medicine, New York, NY., Chakravarti A; Center for Human Genetics and Genomics, NYU Grossman School of Medicine, New York, NY., Niewold TB; Colton Center for Autoimmunity, NYU Grossman School of Medicine, New York, NY.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Nov 02. Date of Electronic Publication: 2021 Nov 02.