Zobrazeno 1 - 5
of 5
pro vyhledávání: '"I. N. Nechaev"'
Autor:
I. N. Nechaev, Vladimir E. Podol'skii, Vladimir V. Galatenko, Alexey E Lebedev, M. Yu. Shkurnikov, E. A. Tonevitskii
Publikováno v:
Bulletin of Experimental Biology and Medicine. 156:706-709
The paper presents a formalized statement of the problem of selecting parameters and construction of a genomic classifier for medical test systems with mathematical methods of machine learning without the use of biological and medical knowledge. A me
Autor:
Andrey Kaprin, Irina Mityakina, Udo Schumacher, Alexander G. Tonevitsky, Maxim Shkurnikov, Vladimir V. Galatenko, Svetlana Zhikrivetskaya, I. N. Nechaev, N. A. Khaustova, Alexey E Lebedev, Timur R. Samatov, D. V. Maltseva
Publikováno v:
BMC Research Notes
Background Inflammatory breast cancer (IBC) is an extremely malignant form of breast cancer which can be easily misdiagnosed. Conclusive prognostic IBC molecular biomarkers which are also providing the perspectives for targeted therapy are lacking so
Autor:
E. K. Saribekyan, M. Yu. Shkurnikov, V. N. Grinevich, N. A. Khaustova, N. A. Savelov, I. N. Nechaev, N. A. Krainova
Publikováno v:
Bulletin of experimental biology and medicine. 155(5)
Inflammatory breast cancer is characterized by high malignancy, early and rapid lymphogenic and hematogenic metastasizing, and high mortality. The diagnosis of this form of cancer is based fully on the clinical criteria. Whole transcriptome analysis
Publikováno v:
Bulletin of experimental biology and medicine. 155(4)
Hyperexpression of HER-2/neu is found in tissues of 25-30% patients with primary breast cancer. Monotherapy with antitumor drug trastuzumab as second-third line therapy and its combination with cytostatics prolong the interval before disease progress
Autor:
D. V. Maltseva, I. N. Nechaev, V. N. Grinevich, N. A. Khaustova, Vladimir V. Galatenko, N. N. Fedotov, Desislava S. Makeeva, M. Yu. Shkurnikov, O. V. Kondrashina, N. A. Savelov
Publikováno v:
Bulletin of experimental biology and medicine. 156(4)
We compared the results of real-time PCR analysis of gene expression in paired specimens breast cancer tissue fixed in RNAlater (Qiagen) stabilization reagent (FF samples) and in formalin (FFPE samples). A clear-cut linear relationship (correlation c