Zobrazeno 1 - 9 of 9 pro vyhledávání: '"I. N. Kurkova"'
1
Robotic QM/MM-driven maturation of antibody combining sites
Autor: Richard A. Lerner, A. V. Stepanova, Matthias Wilmanns, Alexey A. Belogurov, Spyros D. Chatziefthimiou, I. N. Kurkova, Andrey V. Golovin, Alexander G. Gabibov, Ivan V. Smirnov, Yingjie Peng, Olga Zolotareva, G. Michael Blackburn, Natalie A. Ponomarenko
Publikováno v: Science Advances
Science advances 2(10), e1501695-e1501695 (2016). doi:10.1126/sciadv.1501695
Science advances 2(10), e1501695 - e1501695(2016). doi:10.1126/sciadv.1501695
In vitro selection of antibodies from large repertoires of immunoglobulin (Ig) combining sites using combinatorial libraries is a powerful tool, with great potential f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40df0b1edd3cc1b15e24ead90f4e721a
https://doi.org/10.1126/sciadv.1501695
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2
Expression of catalytic antibodies in eukaryotic systems
Autor: T. V. Bobik, A. V. Kaznacheeva, Alexey A. Belogurov, Alexander G. Gabibov, A. V. Zakharov, Ivan V. Smirnov, I. N. Kurkova, Marina V. Serebryakova, Natalia A. Ponomarenko, M. A. Dronina, Alain Friboulet
Publikováno v: Molecular Biology. 45:74-81
Expression of recombinant antibodies in mammalian cells is one of the key problems in immuno-biotechnology. Alternatively, expression of a broad panel of antibodies and of their fragments may be effectively performed in yeast cells. We obtained expre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::def08d415e21af0a61af9889716bfbad
https://doi.org/10.1134/s0026893311010171
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4
Creation of catalytic antibodies metabolizing organophosphate compounds
Autor: Alexey A. Belogurov, Natalia A. Ponomarenko, Ivan V. Smirnov, Alexander G. Gabibov, I. N. Kurkova
Publikováno v: Biochemistry. Biokhimiia. 77(10)
Development of new ways of creating catalytic antibodies possessing defined substrate specificity towards artificial substrates has important fundamental and practical aspects. Low immunogenicity combined with high stability of immunoglobulins in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e361105b37691e2010a0a25125210f0
https://pubmed.ncbi.nlm.nih.gov/23157294
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6
[Expression of the catalytic antibodies in eukaryotic systems]
Autor: A V, Zakharov, I V, Smirnov, M V, Serebriakova, M A, Dronina, A V, Kaznacheeva, I N, Kurkova, A A, Belogurov, A, Friboulet, N A, Ponomarenko, A G, Gabibov, T V, Bobik
Publikováno v: Molekuliarnaia biologiia. 45(1)
Expression of recombinant antibodies in mammalian cells is one of key problems in immunobiotechnology. Alternatively, expression of a broad panel of antibodies and of their fragments may be effectively done in yeast cells. We obtained expression stra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f0985c4b04e8ed7cc02b4dbba18f79b
https://pubmed.ncbi.nlm.nih.gov/21485500
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8
Recognition and degradation of myelin basic protein peptides by serum autoantibodies: novel biomarker for multiple sclerosis
Autor: Sergey V. Suchkov, Kotov Sv, Maria Yu. Zakharova, Bérangère Avalle, I. N. Kurkova, Alain Friboulet, Natalia A. Ponomarenko, Alexander G. Gabibov, Alexander I. Alehin, Daniel Thomas, Herbert C. Morse, Viktor K. Misikov, Ekaterina A. Souslova, Alexey A. Belogurov
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 180(2)
The pathologic role of autoantibodies in autoimmune disease is widely accepted. Recently, we reported that anti-myelin basic protein (MBP) serum Abs from multiple sclerosis (MS) patients exhibit proteolytic activity toward the autoantigen. The aim of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b471c668bd1280b53592345414c72fd
https://pubmed.ncbi.nlm.nih.gov/18178866
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