Zobrazeno 1 - 10
of 79
pro vyhledávání: '"I. Martin Sheldon"'
Autor:
M. Rufaik Farook, Zack Croxford, Steffan Morgan, Anthony D. Horlock, Amy K. Holt, April Rees, Benjamin J. Jenkins, Carmen Tse, Emma Stanton, D. Mark Davies, Catherine A. Thornton, Nicholas Jones, I. Martin Sheldon, Emma E. Vincent, James G. Cronin
Publikováno v:
Molecular Metabolism, Vol 81, Iss , Pp 101900- (2024)
The pyruvate transporter MPC1 (mitochondrial pyruvate carrier 1) acts as a tumour-suppressor, loss of which correlates with a pro-tumorigenic phenotype and poor survival in several tumour types. In high-grade serous ovarian cancers (HGSOC), patients
Externí odkaz:
https://doaj.org/article/3288d1dd7df84df79eb03d5700edacb0
Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
Autor:
Thomas J. R. Ormsby, Sian E. Owens, Matthew L. Turner, James G. Cronin, John J. Bromfield, I. Martin Sheldon
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Treating cell lines with glucocorticoids offers protection against the damage caused by subsequent exposure to selected bacterial pore-forming toxins, and is dependent on the glucocorticoid receptor.
Externí odkaz:
https://doaj.org/article/37c56c1d42024598a0cbc0976eec8687
Autor:
Paula C.C. Molinari, Brittney D. Davidson, Jimena Laporta, Geoffrey E. Dahl, I. Martin Sheldon, John J. Bromfield
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 2, Pp 1464-1474 (2023)
ABSTRACT: Uterine diseases and heat stress (HS) are major challenges for the dairy cow. Heat stress alters host immune resilience, making cows more susceptible to the development of uterine disease. Although HS increases the incidence of uterine dise
Externí odkaz:
https://doaj.org/article/652473a1fe554581a4377708651c8efb
Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells
Publikováno v:
CABI Agriculture and Bioscience, Vol 3, Iss 1, Pp 1-15 (2022)
Abstract Background Bacterial infection of the uterus in postpartum dairy cows limits ovarian follicle growth, reduces blood estradiol concentrations, and leads to accumulation of bacterial lipopolysaccharide (LPS) in ovarian follicular fluid. Althou
Externí odkaz:
https://doaj.org/article/edfd052743ca4683ac765aa7e8a62d92
Autor:
Rachel L. Piersanti, Jeremy Block, Zhengxin Ma, KwangCheol C. Jeong, José E. P. Santos, Fahong Yu, I. Martin Sheldon, John J. Bromfield
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 8, Pp 506-520 (2020)
Abstract Postpartum uterine infection reduces fertility in dairy cattle; however, the mechanisms of uterine infection‐mediated infertility are unknown. Paradoxically, infection‐induced infertility persists after the resolution of disease. Oocytes
Externí odkaz:
https://doaj.org/article/648827987d6c4e318e0690d910ecace4
Autor:
Luisa C. Carneiro, Carmen Bedford, Sarah Jacca, Alfonso Rosamilia, Vera F. de Lima, Gaetano Donofrio, I. Martin Sheldon, James G. Cronin
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Bovine herpesvirus-4 (BoHV-4) and bovine viral diarrhea virus (BVDV) infect the uterus of cattle, often resulting in reduced fertility, or abortion of the fetus, respectively. Here, exposure of primary bovine endometrial cells to BoHV-4 or BVDV modul
Externí odkaz:
https://doaj.org/article/4850b77eca5543159a6aa11e60c3bcde
Autor:
I. Martin Sheldon
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 13-14 (2016)
Externí odkaz:
https://doaj.org/article/ff78428cf3b0423eb48cdbc80cce65d4
Autor:
Paula C.C. Molinari, Brittney D. Davidson, Jimena Laporta, Geoffrey E. Dahl, I. Martin Sheldon, John J. Bromfield
Publikováno v:
Journal of dairy science.
Uterine diseases and heat stress (HS) are major challenges for the dairy cow. Heat stress alters host immune resilience, making cows more susceptible to the development of uterine disease. Although HS increases the incidence of uterine disease, the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd73c98717e7fa4507fddf2b6c30adf8
https://pubmed.ncbi.nlm.nih.gov/36460497
https://pubmed.ncbi.nlm.nih.gov/36460497
Autor:
Daniel J Mathew, Susanta K. Behura, Gilles Charpigny, Lindsay F Grose, I. Martin Sheldon, Patrick Lonergan, James G. Cronin, Heather L Chaney, Thomas E. Spencer
Publikováno v:
Biology of Reproduction
Biology of Reproduction, Society for the Study of Reproduction, 2021, 104 (3), pp.669-683. ⟨10.1093/biolre/ioaa226⟩
Biology of Reproduction, Society for the Study of Reproduction, 2021, 104 (3), pp.669-683. ⟨10.1093/biolre/ioaa226⟩
Bovine endometrium consists of epithelial and stromal cells that respond to conceptus interferon tau (IFNT), the maternal recognition of pregnancy (MRP) signal, by increasing expression of IFN-stimulated genes (ISGs). Endometrial epithelial and strom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f8011f3253c2ae24664e75c139aea4
https://doi.org/10.1093/biolre/ioaa226
https://doi.org/10.1093/biolre/ioaa226
Publikováno v:
Theriogenology. 191
Heat stress and uterine diseases, including metritis and endometritis, both reduce milk yields and reduce reproductive performance. Bacterial growth is promoted by elevated temperature while heat stress reduces host immune cell function, but it is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23865bdac8f49cc41b057ae5384cbc96
https://pubmed.ncbi.nlm.nih.gov/35970030
https://pubmed.ncbi.nlm.nih.gov/35970030