Zobrazeno 1 - 10
of 346
pro vyhledávání: '"I. Magnussen"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 45:87-90
Serum concentrations of diazepam and N-desmethyldiazepam were measured in six adult patients following administration of 10 mg diazepam in solution by the rectal, intravenous, and intramuscular routes. Maximum serum concentrations of 121--200 ng/ml w
Publikováno v:
Acta Pharmacologica et Toxicologica. 49:184-189
Single oral doses of L-5-hydroxytryptophan (5-HTP) were administered in combination with L-aromatic amino acid decarboxylase inhibitors. The time courses of plasma concentrations of 5-HTP, 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-
Autor:
F Engbaek, I Magnussen
Publikováno v:
Acta Pharmacologica et Toxicologica. 43:36-42
5-Hydroxytryptophan has been found to be beneficial when administered alone or in combination with extracerebral aromatic amino acid decarboxylase inhibitors for therapeutic purposes in various disorders in which myoclonus is prominent. In five subje
Autor:
Folmer Nielsen-Kudsk, I. Magnussen
Publikováno v:
Acta Pharmacologica et Toxicologica. 46:257-262
The bioavailability of orally administered L-5-hydroxytryptophan in steady state was investigated at four increasing multiple dose levels in five patients suffering from various myoclonic disorders. An L-aromatic amino acid decarboxylase inhibitor wa
Publikováno v:
Nielsen-Kudsk, F, Magnussen, I, Jensen, T S & Naeser, K 1980, ' Bioavailability and pharmacokinetics in man of orally administered theophylline ', Acta pharmacologica et toxicologica, vol. 46, no. 3, pp. 205-12 .
The pharmacokinetics of theophylline after both intravenous and oral administration was investigated in six hospitalized patients with normal renal, hepatic and pulmonary functions. A rather wide range of biological half-lives from about 3-16 hours a
Autor:
I. Magnussen, Folmer Nielsen-Kudsk
Publikováno v:
Acta Pharmacologica et Toxicologica. 44:308-314
The pharmacokinetics of 5-hydroxytryptophan were investigated in relation to intravenous administration of single doses of the amino acids (0.2 mg/kg b.wt.) to five patients pretreated for one week with carbidopa, an L-aromatic amino acid decarboxyla
Autor:
I. Magnussen
Publikováno v:
Acta Pharmacologica et Toxicologica. 55:199-202
The concentration of L-5-hydroxytryptophan (5-HTP) was measured in plasma and whole brain tissue from mice by use of high pressure liquid chromatography with fluorimetric detection after reaction with phthaldialdehyde. 5-HTP was injected intraperiton
Publikováno v:
Acta Neurologica Scandinavica. 56:29-36
In an open preliminary study theophyllamine (theophylline-ethylenediamine) was administered to eight patients with idiopathic parkinsonism showing residual signs of parkinsonism though already in treatment with levodopa. Although theophyllamine in pr
Autor:
Palle Juul-Jensen, K. Lundbak, Aa. Prange Hansen, I. Magnussen, E. Dupont, B. De Fine Olivarius
Publikováno v:
Acta Neurologica Scandinavica. 57:488-493
The growth hormone release inhibiting hormone acts probably both as a true hypophysiotropic hormone and as a neuroregulatory substance. Neurophysiological studies have shown that somatostatin is a CNS depressant. Somatostatin might therefore be of th
Autor:
Lotte Lauritzen, Erik Dupont, B. Christensen, Per Soelberg Sørensen, I. Magnussen, L. Bayer, J Boas, E.R. Hansen, Niels Peter Utzon, B. Mikkelsen, Lene Wermuth, Per Bech, J. Worm-Petersen, S. Timm
Publikováno v:
Wermuth, L, Sørensen, P S, Timm, S, Christensen, B, Utzon, N P, Boas, J, Dupont, E, Hansen, E, Magnussen, I, Mikkelsen, B, Worm-Petersen, J, Lauritzen, L, Bayer, L & Bech, P 1998, ' Depression in idiopathic Parkinson's disease treated with citalopram : A placebo-controlled trial ', Nordic Journal of Psychiatry, vol. 52, no. 2, pp. 163-169 . https://doi.org/10.1080/08039489850139049
The antidepressive effect of citalopram in depressed patients with idiopathic Parkinson's disease (PD) was evaluated in a placebo-controlled trial. Before treatment the patients had a mean Hamilton Depression Scale (HAM-D) score around 17. In the acu