Zobrazeno 1 - 10
of 20
pro vyhledávání: '"I. M. PRITTS"'
Autor:
I. M. Pritts, L. C. Fisher, Teresa L. Neeper-Bradley, Timothy D. Landry, Rochelle W. Tyl, Patricia E. Losco, Darol E. Dodd, James P. Lyon
Publikováno v:
Toxicological Sciences. 52:258-268
Twenty-eight 42-day-old pups/sex/group (F0) were exposed to toluene diisocyanate vapor (TDI; 80% 2,4-TDI, 20% 2,6-TDI) by inhalation at 0.0, 0.02, 0.08, or 0.3 ppm, 6 h/day, 5 days/week, for 10 weeks, then mated within groups for 3 weeks, with exposu
Autor:
Bryan Ballantyne, I. M. Pritts, R. W. Tyl, Dennis R. Klonne, Darol E. Dodd, L. C. Fisher, Patricia E. Losco, D. L. Fait
Publikováno v:
Toxicological Sciences. 27:49-62
Ethylene glycol (EG; CAS No. 107-21-1) is teratogenic to mice by whole-body (WB) exposure to aerosol (1000-2500 mg/m3). The WB results were confounded by possible exposure from ingestion after grooming and/or from percutaneous absorption. Therefore,
Autor:
D. L. Fait, L. C. Fisher, R. W. Tyl, Dennis R. Klonne, Darol E. Dodd, Bryan Ballantyne, I. M. Pritts, T. A. Savine
Publikováno v:
Toxicological Sciences. 24:57-75
Ethylene glycol (EG) is a major industrial chemical, shown to be teratogenic at high doses by gavage in rodents. Since one route of industrial exposure is to the aerosol at high concentrations, timed-pregnant CD rats and CD-1 mice were exposed, whole
Autor:
D. L. Fait, Bryan Ballantyne, L. C. Fisher, T. A. Savine, R. W. Tyl, I. M. Pritts, Darol E. Dodd
Publikováno v:
Toxicological Sciences. 23:251-260
Evaluation of Exposure to Water Aerosol or Air by Nose-Only or Whole-Body Inhalation Procedures for CD-1 Mice in Developmental Toxicity Studies. Tyl, R. W., Ballantyne, B., Fisher, L. C., Fait, D. L., Savine, T. A., Pritts, I. M., and Dodd, D. E. (19
Autor:
Darol E. Dodd, L. C. Fisher, Rochelle W. Tyl, Patricia E. Losco, Catherine M. Troup, James P. Lyon, Timothy D. Landry, I. M. Pritts, Mildred F. Kubena
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 52(2)
Mated female CD® (Sprague-Dawley) rats, 25/group, were exposed to toluene diisocyanate (TDI) vapor, for six h/day on gestational days (gd) 6 through 15, at 0.00, 0.02, 0.10, or 0.50 p.p.m., Maternal clinical signs, body weights, and feed and water c
Publikováno v:
Journal of applied toxicology : JAT. 17
Methyl tertiary-butyl ether (MTBE) is an oxygenate that is added to gasoline to boost octane and enhance combustion, thereby reducing carbon monoxide and hydrocarbon tailpipe emissions. The acute and subchronic neurotoxicity of MTBE were evaluated in
Autor:
Catherine M. Troup, William M. Snellings, Bryan Ballantyne, Robert H. Garman, I. M. Pritts, Darol E. Dodd
Publikováno v:
Fundamental and Applied Toxicology. 7:329-339
Fischer-344 rats, in groups of 10 males and 10 females, were exposed for 9 days (6 hr/day) to 2,4-pentanedione (2,4-PD) vapor at mean concentrations of 805, 418, 197, and 0 (control) ppm. No deaths occurred, and the only adverse signs were of sensory
Publikováno v:
Fundamental and Applied Toxicology. 10:20-39
Pregnant Fischer 344 rats and New Zealand white rabbits were exposed to 2-ethoxyethanol acetate (EEA; CAS No. 111–159) vapor by inhalation on Gestational Days 6 through 15 (rats) or 6 through 18 (rabbits) at concentrations of 0, 50, 100, 200, or 30
Autor:
Edward H. Fowler, Darol E. Dodd, R. W. Tyl, James P. Lyon, William M. Snellings, G. Kimmerle, F. O. O'neal, I. M. Pritts
Publikováno v:
Fundamental and Applied Toxicology. 8:493-505
A two-generation reproduction study was performed by exposure of Sprague-Dawley CD rats to concentrations of 40, 10, 1, or 0 (control) ppm of nitrobenzene (NB) vapor. No NB-related effects on reproduction were observed at 10 or 1 ppm. At 40 ppm, a de
Publikováno v:
Fundamental and Applied Toxicology. 8:310-327
Pregnant Fischer 344 rats and CD-1 mice were exposed to methyl isobutyl ketone vapor (CAS No. 108-10-1) by inhalation on Gestational Days 6 through 15 at concentrations of 0, 300, 1000, or 3000 ppm (mean analytical values of 0, 305, 1012, and 2997 pp