Zobrazeno 1 - 10
of 45
pro vyhledávání: '"I. M. Kuznetsova"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 173:146-150
Publikováno v:
Bulletin of experimental biology and medicine. 173(1)
Most drugs are metabolized in the liver, which can lead to their activation or inactivation with a change in the parent compound pharmacology, as well as liver damage by active metabolites. Preclinical animal studies of drug safety do not always pred
Autor:
Anna I. Sulatskaya, Konstantin K. Turoverov, Olga I. Povarova, Iu A Antifeeva, Natalia P. Rodina, I M Kuznetsova, Maksim I. Sulatsky
In this work α-synuclein amyloid fibrils, formation of which is a biomarker of the Parkinson’s disease, were investigated with the use of fluorescent probe thioflavin T (ThT). Experimental conditions of the protein fibrillogenesis were chosen so t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ef0373515cf1937ddc1d43cec3ca0b
Publikováno v:
Biofizika. 61(2)
Osmolytes are molecules with the function among others to align hydrostatic pressure between intracellular and extracellular spaces. Accumulation of osmolytes occurs in the cell in response to stress caused by pressure change, change in temperature,
Autor:
S N Gvasaliya, I M Kuznetsova, Seiji Kojima, Konstantin K. Turoverov, I. L. Sashin, S. G. Lushnikov, A. V. Svanidze
Publikováno v:
Ferroelectrics. 348:154-160
Inelastic incoherent neutron scattering in hen egg white lysozyme, alpha-chymotrypsin from bovine pancreas, and human serum albumin has been investigated. The effect of the isotopic hydrogen-deuterium exchange on the vibrational spectrum of lysozyme
Autor:
A I, Sulatskaia, E A, Volova, Ia Iu, Komissarchik, E S, Snigirevskaia, A A, Maskevich, E A, Drobchenko, I M, Kuznetsova, K K, Turoverov
Publikováno v:
Tsitologiia. 55(11)
Investigation of the structure of ordered protein aggregates--amyloid fibrils, the influence of the native structure of the protein and the environment on the process of fibrillation is currently the subject of intensive research. The present work is
Autor:
T P, Amen, E V, Mikhaĭlov, V V, Alenin, A V, Artemov, P A, Dement'ev, M A, Khodorkovskiĭ, T O, Artamonov, I M, Kuznetsova, T R, Soĭdla, O V, Nevzgliadova
Publikováno v:
Tsitologiia. 54(11)
Structural and functional characteristics of the yeast red pigment (product of polymerization of N1-(beta-D-ribofuranosyl)-5-aminoimadazole), isolated from adel 1 mutant cells of Saccharomyces cerevisiae, its deribosylated derivatives (obtained by ac
Autor:
A I, Sulatskaia, I M, Kuznetsova
Publikováno v:
Tsitologiia. 52(11)
Benzthiazole dye thioflavin T (ThT) is widely used to study the formation and structure of amyloid fibrils. Nevertheless, till now there is no common opinion concerning molecular mechanisms of ThT binding to amyloid fibrils and the reasons of dramati
Autor:
O V, Nevzgliadova, A V, Artemov, A G, Mittenberg, E V, Mikhaĭlova, I M, Kuznetsova, K K, Turoverov, T R, Soĭdla
Publikováno v:
Tsitologiia. 52(1)
Amyloid bound thioflavine T fluorescence was studied in the lysates of yeast strains carrying mutations in genes ADE1 or ADE2 and accumulating red pigment, a result of polymerization of aminoimidazoleribotide (an intermediate of adenine biosynthesis)
Autor:
O V, Nevzgliadova, A V, Artemov, A G, Mittenberg, E I, Kostyleva, E V, Mikhaĭlova, K V, Solov'ev, I M, Kuznetsova, K K, Turoverov, T R, Soĭdla
Publikováno v:
Tsitologiia. 52(1)
A new approach: comparative analysis of proteins of the pellets of crude cell lysates of isogenic strains of Saccharomyces cerevisiae differing by their prion composition permitted to identify a large group of prion-associated proteins in yeast cells