Disease-modifying anti-rheumatic drugs: Strategies for screening

Autor: I. M. Hunneyball, M. J. Crossley, J.G. Bowen

Publikováno v: Pharmacology & Therapeutics. 56:287-306

Rheumatoid arthritis, a disease of unknown aetiology, has a multifactorial pathogenesis which may result in irreversible connective tissue destruction and loss of joint function. The search for drugs which offer more than symptomatic relief is a long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7711b0d08d15b93396f707a32b24ebc4
https://doi.org/10.1016/0163-7258(92)90021-q

Pharmacological studies of antigen-induced arthritis in BALB/c mice II. The effects of second-line antirheumatic drugs and cytotoxic agents on the histopathological changes

Autor: M. J. Crossley, I. M. Hunneyball, M. Spowage

Publikováno v: Agents and Actions. 18:394-400

The effects of treatment with second-line antirheumatic drugs and cytotoxic agents on the severity of experimental monoarticular arthritis in BALB/c mice have been investigated. The arthritis was assessed histologically in terms of synovitis and eros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a2a6d8bf12382278940ad83b68ab05
https://doi.org/10.1007/bf01965003

Eular workshop on Rheumatology Research

Autor: A. Bjelle, B. Cedergren, L. Wählby, A. P. Th. Boerbooms, P. J. Geerdink, L. B. A. van de Putte, F. A. M. Ouweland, R. R. C. Buchanan, A. Morgan, N. A. Staines, P. J. W. Venables, R. N. Maini, R. C. Bucknall, P. A. Bacon, J. Verrier Jones, M. Leirisalo, O. Laitinen, M. Bühring, C. Rosak, W. Stöckle, W. Magnet, L. J. Catogio, R. M. Bernstein, C. M. Black, G. R. V. Hughes, P. J. Maddison, P. J. Charles, Yi. Tung, R. C. Buchanan, H. Deicher, E. Weißbarth, J. Zeller, B. Baruth, F. Delbarre, A. de Gery, A. Kahan, E. de Vries, C. J. P. van der Veen, J. P. van der Weij, F. Klein, A. M. de Bruijn, A. Cats, R. Dreher, null Coworkers, M. Duclos, H. Peter, H. Zeidler, P. Rieber, J. Pichler, W. Limany, N. Dunn, N. P. Hurst, E. Denholm, G. Nuki, A. Ebringer, J. Hayes, P. Cowling, R. Ebringer, T. Egeland, Ø. Forre, J. J. M. Festen, F. H. Kuipers, A. H. Schaars, Ø. Førre, K. Waalen, O. J. Mellbye, K. Froebel, D. Lewis, R. D. Sturrock, R. Goldschmeding, P. C. Limburg, G. W. Pastoor, P. M. Houtman, C. G. M. Kallenberg, P. Halberg, I. Lorenzen, J. Bennedsen, J. M. Rhodes, N. D. Hall, L. -J. Eales, D. R. Blake, I. M. Hunneyball, K. Helmke, T. Boeder, J. Teuber, P. Hermanns, E. M. Veys, G. Verbruggen, A. C. Horsfall, P. A. Mumford, L. Schrieber, O. Huber, H. Kluin-Nelemans, J. Vernooy, F. Gmelig Meyling, R. Derksen, L. Kater, G. Husby, J. T. Gran, E. Thorsby, G. D. Johnson, D. R. Bainbridge, E. J. Holborow, M. Bubel, D. H. Goddard, J. Jonsson, R. Norberg, W. Schilling, R. Kalden, O. Leitner, B. Manger, A. Beck, B. Koch, M. C. J. M. de Jong, T. Walstra, J. van der Meulen, M. Kávai, A. Bányai, A. Zsindely, I. Sonkoly, Gy. Szegedi, L. Klareskog, U. Forsum, A. Scheynius, D. Kabelitz, H. Wigzell, P. Koivuranta, H. Repo, U. Kiistala, P. Österman, Y. Konttinen, C. Friman, E. Tolvanen, E. Johansson, Y. T. Konttinen, S. Reitamo, A. Seppä, M. Malmström, F. Lindström, H. Hellquist, J. Olofsson, PJ. Maddison, CM. Black, MIV Jayson, J. R. Batchelor, Kl. Walsh, RM Bernstein, LJ. Catoggio, CD. Holland, GRV Hughes, J. M. Mbuyi, J. Dequeker, Ö Förre, W. Johnsen, C. J. L. M. Meijer, C. de Graaf-Reitsma, G. J. M. Lafeber, O. Meyer, O. Borda-Oriarte, T. Haïm, A. Ryckewaert, H. Mielants, M. Van Steenkiste, J. De Langhe, M. Moutsopoulos, J. Hooks, P. Mumford, V. Patel, G. S. Panayi, D. Piatier-Tonneau, P. S. Mach, C. Plater-Zyberk, M. Clarke, F. Raeman, W. De Cock, J. Leempoels, J. De Cree, H. Verhaegen, A. Ranki, T. Paavonen, U. Kankaanpää, E. Nilsson, G. Biberfeld, G. Room, J. G. Saal, F. Frank, H. Rauteenstrauch, M. Hadam, P. Fritz, W. Laschner, R. J. Scheper, B. M. E. von Blomberg-van der Flier, G. H. Boerrigter, D. van Bruynzeel, A. C. H. M. van Dinther-Janssen, K. H. Simon, R. E. Schmidt, C. C. Erhardt, R. D. Melsom, J. McCarthy, R. Smeenk, G. Van der Lelij, L. Aarden, N. D. Staite, H. E. Stierle, K. A. Brown, J. D. Perry, A. J. G. Swaak, J. Groenwold, R. J. T. Smeenk, G. H. Toenes, H. H. Edel, K. Eggert, E. Held, F. K. Hübner, M. Schattenkirchner, O. Wegelius, F. Tron, L. Jacob, J. F. Bach, J. W. Lens, W. B. van den Berg, M. H. van Rijswijk, M. A. van Leeuwen, M. van der Giessen, T. H. The, W. J. van Venrooij, C. A. G. van Eekelen, W. J. A. Habets, M. H. L. Salden, D. J. de Rooij, P. Van Wanghe, Ph. Hermanns, Ph. Van Bruwaene, G. De Brabanter, D. De Landsheere, C. Immesoete, M. J. F. Walravens, E. Stevens, H. Warnatz, G. Lemm, A. Wiik, J. Petersen, H. Permin, F. A. Wollheim, J. Carlsson, A. Forsgren, H. Pettersson, P. Youinou, P. Miossec, P. Le Goff

Publikováno v: Clinical Rheumatology. 1:47-78

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::764ec7190d614550fdb65dcbc253cb72
https://doi.org/10.1007/bf02032477

Sendai-viral HN and F glycoproteins as probes of plasma-membrane protein catabolism in HTC cells. Studies with fusogenic reconstituted Sendai-viral envelopes

Autor: E. Ellen Billett, R T Earl, Mayer Rj, I M Hunneyball

Publikováno v: Biochemical Journal. 241:801-807

Reconstituted Sendai-viral envelopes (RSVE) were produced by the method of Vainstein, Hershkovitz, Israel & Loyter [(1984) Biochim. Biophys. Acta 773, 181-188]. RSVE are fusogenic unilamellar vesicles containing two transmembrane glycoproteins: the H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07da617c01e1bab49c1793149adc6733
https://doi.org/10.1042/bj2410801

Albumin microspheres for intra-articular drug delivery: investigation of their retention in normal and arthritic knee joints of rabbits

Autor: Alan Smith, Clive G. Wilson, J H Ratcliffe, S.S. Davis, I M Hunneyball

Publikováno v: The Journal of pharmacy and pharmacology. 39(4)

The retention of 131I-labelled albumin microspheres and microsphere-entrapped [131I]rose bengal was investigated in normal and experimentally arthritic knee joints of rabbits. Albumin microspheres were cleared slowly from the joint cavity and no sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af5e9f297942a59cc10695650c363e5
https://pubmed.ncbi.nlm.nih.gov/2884293