Zobrazeno 1 - 10
of 54
pro vyhledávání: '"I. L. Valuev"'
Publikováno v:
Polymer Science, Series B. 64:354-357
A method to increase the thromboresistance of the biospecific antiproteinase hemosorbent was suggested based on simultaneous immobilization of duck egg ovomucoid and blood anticoagulant—heparin or hirudin—in the bulk of polyacrylamide hydrogel. I
Publikováno v:
Polymer Science, Series B. 63:531-535
The copolymers of methacryloylguanidine hydrochloride with methacrylamide and diallyldimethylammonium chloride are synthesized by radical polymerization. The reactivity ratios of these monomers are determined, and the dependence of the biocidal activ
Publikováno v:
Polymer Science, Series B. 63:404-407
The effect of the chemical structure of crosslinking agents on the activity of proteins in hydrogels obtained by the copolymerization of acrylamide, a crosslinking agent, and an unsaturated protein derivative is studied. It is shown that interaction
Publikováno v:
Applied Biochemistry and Microbiology. 57:373-376
The effect of the structure of a mucoadhesive, insulin-containing, polymeric hydrogel on the rate of hormone release was studied. It has been shown that a decrease in the pore size of the hydrogel leads to an increase in the rate of insulin release,
Publikováno v:
Applied Biochemistry and Microbiology. 56:505-511
On the example of published and new experimental data, it was shown that insulin-containing hydrogels based on copolymers of N-(2-D-glucose)acrylamide and acrylamide crosslinked by Concanavalin A can simulate one of the functions of the pancreas, i.e
Publikováno v:
Applied Biochemistry and Microbiology. 56:29-31
The dependence of the activity of immobilized trypsin on the conformation of the polymer carrier macromolecule was studied. Fluorescence spectroscopy shows that immobilization of the enzyme on a rigid polymer chain prevents the association of enzyme
Publikováno v:
Polymer Science, Series B. 61:637-641
This survey summarizes the published and new results of research conducted in leading scientific institutions and clinics in our country. It was shown that the oral administration of dilute solutions of insulin does not cause the destruction of the h
Publikováno v:
Pharmaceutical Chemistry Journal. 53:298-301
A new approach for delivering insulin into the bloodstream through the gastrointestinal system after peroral administration of diluted insulin solutions to animals with experimental diabetes was studied. It was shown that such solutions provided a ph
Publikováno v:
Applied Biochemistry and Microbiology. 55:371-374
The potential use of sodium-alginate hydrogels as mucoadhesive drug delivery carriers for intranasal application is studied. It is demonstrated that the drug release rate is dependent on the drug solubility in water, the drug concentration in the car
Publikováno v:
Polymer Science, Series A. 61:292-295
The possibility of creating acid-stable polymeric insulin carriers capable of swelling in a weakly alkaline medium and being adsorbed on the intestinal walls with insulin release has been studied. In vitro and in vivo experiments have shown that the