Zobrazeno 1 - 10
of 17
pro vyhledávání: '"I. L. Grupp"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H1759-H1766
In the present study, isolated dog and rat hearts were perfused in the Langendorff mode with Krebs bicarbonate buffer in the absence and presence of 10(-5) M oligomycin. The perfusion protocols employed allowed tissue pH to drop during subsequent isc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873e88685d23a6fe3f1723fb69d39bf5
https://doi.org/10.1152/ajpheart.1990.259.6.h1759
https://doi.org/10.1152/ajpheart.1990.259.6.h1759
Autor:
J N, Muth, H, Yamaguchi, G, Mikala, I L, Grupp, W, Lewis, H, Cheng, L S, Song, E G, Lakatta, G, Varadi, A, Schwartz
Publikováno v:
The Journal of biological chemistry. 274(31)
The L-type voltage-dependent calcium channel (L-VDCC) regulates calcium influx in cardiac myocytes. Activation of the beta-adrenergic receptor (betaAR) pathway causes phosphorylation of the L-VDCC and that in turn increases Ca(2+) influx. Targeted ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a0cfa4bb7ae2061100c69a56c054297
https://pubmed.ncbi.nlm.nih.gov/10419451
https://pubmed.ncbi.nlm.nih.gov/10419451
Publikováno v:
Alterations of Excitation-Contraction Coupling in the Failing Human Heart ISBN: 9783642486722
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5aed92bea0ec61bae6c3170f1f3cc8
https://doi.org/10.1007/978-3-642-48670-8_3
https://doi.org/10.1007/978-3-642-48670-8_3
Autor:
J, Neumann, T, Eschenhagen, I L, Grupp, A, Haverich, J W, Herzig, S, Hirt, P, Kalmár, W, Schmitz, H, Scholz, B, Stein, H, Wenzlaff, N, Zimmermann
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(3)
In trabeculae carneae from failing human myocardium, CGP 48506 increased the force of contraction, which reached 310 +/- 41% of predrug values at 100 mumol/l. Its stereoisomer CGP 48508 did not affect the force of contraction (100 mumol/l). The posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c57f3ab723cc6f5ba32fee89dd59222
https://pubmed.ncbi.nlm.nih.gov/8667226
https://pubmed.ncbi.nlm.nih.gov/8667226
Publikováno v:
Cellularmolecular biology research. 41(6)
Our objective was to test the hypothesis that, via transgenesis, one can modify the contractile protein complement of the mouse heart. Using a promoter derived from the mouse myosin heavy chain gene (alpha-MyHC), we attempted to remodel the mouse myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9525360549f0b790a5049223882cc0c
https://pubmed.ncbi.nlm.nih.gov/8777429
https://pubmed.ncbi.nlm.nih.gov/8777429
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 220(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0872ab780fac9315656b66459d668058
https://pubmed.ncbi.nlm.nih.gov/6273527
https://pubmed.ncbi.nlm.nih.gov/6273527
Publikováno v:
Arzneimittel-Forschung. 34(3A)
3,4-Dihydro-6-[4-(3,4- dimethoxybenzoyl )-1-piperazinyl]-2(1H)- qu inolinone ( OPC -8212) has positive inotropic effects in guinea pig and dog isolated heart preparations. The rat heart ventricle does not respond to OPC -8212 but the atria do. OPC -8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c4f77deeefb937cd9753876600e45fa
https://pubmed.ncbi.nlm.nih.gov/6540089
https://pubmed.ncbi.nlm.nih.gov/6540089
Publikováno v:
Progress in clinical and biological research. 258
From the results of this study the following significant conclusions can be drawn. First, there are two separate inotropic responses to ouabain in the rat ventricle and the isolated rat heart resulting in a biphasic dose-response curve. Second, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e94ae3d86b55c30bce55e67de0efce6
https://pubmed.ncbi.nlm.nih.gov/2837773
https://pubmed.ncbi.nlm.nih.gov/2837773
Publikováno v:
Molecular pharmacology. 20(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fce3b3b93ad19d8fe40576b44a3a9c97
https://pubmed.ncbi.nlm.nih.gov/6173736
https://pubmed.ncbi.nlm.nih.gov/6173736
Publikováno v:
Bayer-Symposium ISBN: 9783642705014
The recent discovery of the dihydropyridine derivatives Bay k 8644 [55, 56, 62] YC-170 [61] and CGP 28392 [14, 68] together with the well-known nifedipine-like drugs have provided an avenue for a classification of dihydropyridines (DHPs) into two sep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3cbf76938c54e8ef49bbfffaee6483
https://doi.org/10.1007/978-3-642-70499-4_10
https://doi.org/10.1007/978-3-642-70499-4_10