Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors

Autor: K. Schroeder, K.D. Bremm, N. Alépée, J.G.M. Bessems, B. Blaauboer, S.N. Boehn, C. Burek, S. Coecke, L. Gombau, N.J. Hewitt, J. Heylings, J. Huwyler, M. Jaeger, M. Jagelavicius, N. Jarrett, H. Ketelslegers, I. Kocina, J. Koester, J. Kreysa, R. Note, A. Poth, M. Radtke, V. Rogiers, J. Scheel, T. Schulz, H. Steinkellner, M. Toeroek, M. Whelan, P. Winkler, W. Diembeck

Publikováno v: TOXICOLOGY IN VITRO
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Toxicology in Vitro; Vol 25
Toxicology in Vitro

There are now numerous in vitro and in silico ADME alternatives to in vivo assays but how do different industries incorporate them into their decision tree approaches for risk assessment, bearing in mind that the chemicals tested are intended for wid

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