Zobrazeno 1 - 10
of 23
pro vyhledávání: '"I. Kh. Kaufman"'
We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spectrum with contributions including the dehydration amongst species, inte
Externí odkaz:
http://arxiv.org/abs/1704.03267
Publikováno v:
New Journal of Physics, Vol 17, Iss 8, p 083021 (2015)
Biological ion channels are protein nanotubes embedded in, and passing through, the bilipid membranes of cells. Physiologically, they are of crucial importance in that they allow ions to pass into and out of cells, fast and efficiently, though in a h
Externí odkaz:
https://doaj.org/article/a417db6d44cb4818b00748c335c31a3d
Autor:
Peter V. E. McClintock, Olena Fedorenko, Miraslau L. Barabash, W. A. T. Gibby, I. Kh. Kaufman, Dmitry G. Luchinsky, Stephen K. Roberts
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1862(9)
Mutation-induced transformations of conductivity and selectivity in NaChBac bacterial channels are studied experimentally and interpreted within the framework of ionic Coulomb blockade (ICB), while also taking account of resonant quantised dehydratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69082906ebf971e7bff5a55c9096362
https://pubmed.ncbi.nlm.nih.gov/32360369
https://pubmed.ncbi.nlm.nih.gov/32360369
Autor:
Peter V. E. McClintock, W. A. T. Gibby, Dmitry G. Luchinsky, I. Kh. Kaufman, Dogan A. Timucin
Publikováno v:
2017 International Conference on Noise and Fluctuations (ICNF).
To establish the general statistical mechanical properties of highly conductive but selective nano-filters we develop an equilibrium statistical-mechanical theory of the KcsA filter, find the probabilities for the filter to bind ions from the mixed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e290bcf63e3422574e9e7bd2b0bfa1e9
https://doi.org/10.1109/icnf.2017.7985973
https://doi.org/10.1109/icnf.2017.7985973
Publikováno v:
Lancaster University-Pure
We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spectrum with contributions including the dehydration amongst species, inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bf47469272fa62d01323234ebaa686
https://eprints.lancs.ac.uk/id/eprint/86242/
https://eprints.lancs.ac.uk/id/eprint/86242/
Ionic Coulomb blockade (ICB) is an electrostatic phenomenon recently discovered in low-capacitance ion channels/nanopores. Depending on the fixed charge that is present, ICB strongly and selectively influences the ease with which a given type of ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bb458d9a7dd6b399e63318ad974a6a
https://eprints.lancs.ac.uk/id/eprint/86245/
https://eprints.lancs.ac.uk/id/eprint/86245/
Autor:
W. A. T. Gibby, Peter V. E. McClintock, I. Kh. Kaufman, Dmitry G. Luchinsky, Robert S. Eisenberg
The highly selective permeation of ions through biological ion channels can be described and explained in terms of fluctuational dynamics under the influence of powerful electrostatic forces. Hence valence selectivity, e.g. between Ca2+ and Na+ in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a4a6ef24f1fe7c6fe78abdc1b39e23
https://doi.org/10.1088/1742-5468/2016/05/054027
https://doi.org/10.1088/1742-5468/2016/05/054027
Biological ion channels are protein nanotubes embedded in, and passing through, the bilipid membranes of cells. Physiologically, they are of crucial importance in that they allow ions to pass into and out of cells, fast and efficiently, though in a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f86b1370d67002328a9e61f125760a0
https://doi.org/10.1088/1367-2630/17/8/083021
https://doi.org/10.1088/1367-2630/17/8/083021
Autor:
W. A. T. Gibby, Dmitry G. Luchinsky, Peter V. E. McClintock, I. Kh. Kaufman, Robert S. Eisenberg
Publikováno v:
2015 International Conference on Noise and Fluctuations (ICNF).
The conduction and selectivity of calcium/sodium ion channels are described in terms of ionic Coulomb blockade, a phenomenon based on charge discreteness, an electrostatic exclusion principle, and stochastic ion motion through the channel. This novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2d9b4ee3b8287b4b1f70b02571cf67
https://doi.org/10.1109/icnf.2015.7288558
https://doi.org/10.1109/icnf.2015.7288558
Publikováno v:
Physical Review Letters. 84:2556-2559
Fluctuational escape from a multiwell potential is shown to display new features, as compared to the conventional single-well case. The flux J may depend on friction Gamma exponentially strongly, over an exponentially long period; for small enough te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ec1a2688186ff60667140da3ef570f
https://doi.org/10.1103/physrevlett.84.2556
https://doi.org/10.1103/physrevlett.84.2556