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pro vyhledávání: '"I. Kempen"'
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Autor:
Michèle Reboud-Ravaux, Bernard Pirotte, Xiao Tan, Jean-François Renard, Maurice Pagano, I. Kempen, Feryel Soualmia, Laetitia Furio, Lixian Qin, Alain Hovnanian, Chahrazade El Amri
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (2), pp.598-612. ⟨10.1021/jm500988d⟩
Journal of Medicinal Chemistry, 2015, 58 (2), pp.598-612. ⟨10.1021/jm500988d⟩
Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (2), pp.598-612. ⟨10.1021/jm500988d⟩
Journal of Medicinal Chemistry, 2015, 58 (2), pp.598-612. ⟨10.1021/jm500988d⟩
International audience; The inhibition of kallikreins 5 and 7, and possibly kallikrein 14 and matriptase, (that initiates the kallikrein proteolytic cascade) constitutes an innovative way to treat some skin diseases such as Netherton syndrome. We pre
Autor:
Agnès Noël, Silvia Blacher, Francis Frankenne, Stéphane Counerotte, Pascal De Tullio, Marc Hemmer, Lionel Pochet, Jean-Michel Foidart, Bernard Pirotte, I. Kempen
Publikováno v:
European journal of medicinal chemistry / Chimica therapeutica. 43(12):2735-2750
Novel 6-substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid derivatives were synthesized and their potency in reducing the invasive behaviour of HT 1080 fibrosarcoma cells was evaluated. Structure-activity relationships were deduced from biological r
Autor:
D. Papapostolou, N. Thierry, Lionel Pochet, Michèle Reboud-Ravaux, Jean-Michel Foidart, Agnès Noël, Bernard Masereel, Stéphane Counerotte, I. Kempen, Bernard Pirotte
Publikováno v:
British Journal of Cancer
University of Namur
University of Namur
In search for new anticancer agents, we have evaluated the antiinvasive and antimigrative properties of recently developed synthetic coumarin derivatives among which two compounds revealed important activity: 3-chlorophenyl 6-acetoxymethyl-2-oxo-2H-1
Autor:
Silvia Blacher, Pascal De Tullio, Francis Frankenne, Marc Hemmer, Jean-Michel Foidart, Jean-Luc Bueb, Eric Tschirhart, I. Kempen, Agnès Noël, Vincent Lambert, Bernard Pirotte
Publikováno v:
Drug Development Research.
The development of blood vessels inside tumors is required to provide the nutrients and oxygen needed for tumor growth and to allow the spread of cancer cells at a distance to form metastasis. Angiogenesis is also implicated in ocular diseases like a
Publikováno v:
Journal of psychosomatic research. 51(5)
The aim of the present study is to increase knowledge regarding associations between couples' health condition and psychological distress in both spouses considering gender as well as patient/spouse status.We examined a community-based sample of 995
Publikováno v:
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 9(7)
Though health-related quality of life (HRQoL) is now commonly measured as an outcome in clinical trials, the relationships between its components remain unclear. The relation of physical symptoms, physical function, and psychological symptoms to each
Publikováno v:
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 9(4)
This article examines the influence of three pre-morbidly assessed psychological attributes (i.e. neuroticism, mastery and self-efficacy expectancies) on functional decline after congestive heart failure (CHF; n = 134) and acute myocardial infarction
Autor:
N, Steverink, G I, Kempen
Publikováno v:
Tijdschrift voor gerontologie en geriatrie. 29(4)
Which factors other than age play a role in the future time perspective of elderly people? In the literature no consensus exists on these factors. Besides, the usual approach of future time perspective as 'extension' seems limited and less suited for
Autor:
G I, Kempen, J, Ormel
Publikováno v:
International journal of geriatric psychiatry. 13(7)
The purpose of this study was to examine the independent contributions of physical performance and cognitive status to subsequent levels of ADL disability in low-functioning non-institutionalized older adults.A prospective cohort study included 416 w