Zobrazeno 1 - 10
of 306
pro vyhledávání: '"I. Ju Chen"'
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 1, Pp 38-47 (2024)
Background: Immunomodulatory agents, such as tocilizumab (TCZ), exert promising effects against SARS-CoV-2 infection. However, growing evidence indicates that using TCZ may carry higher risks of secondary bloodstream infection (sBSI). This study dete
Externí odkaz:
https://doaj.org/article/e440fa8f60874966a30f9b3fb42c40e2
Autor:
Huei-Jen Chen, Yi-An Cheng, Yu-Tung Chen, Chia-Ching Li, Bo-Cheng Huang, Shih-Ting Hong, I.-Ju Chen, Kai-Wen Ho, Chiao-Yun Chen, Fang-Ming Chen, Jaw-Yuan Wang, Steve R. Roffler, Tian-Lu Cheng, Tung-Ho Wu
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background PEGylated nanoparticles (PEG-NPs) are not effective for hematologic malignancies as they lack the enhanced permeability and retention effect (EPR effect). Tumor-targeted PEG-NPs can systemically track lymphoma and actively interna
Externí odkaz:
https://doaj.org/article/d7e948b59260455786e1f5ea63ad1238
Autor:
Huei-Jen Chen, Yi-An Cheng, Yu-Tung Chen, Chia-Ching Li, Bo-Cheng Huang, Shih-Ting Hong, I.-Ju Chen, Kai-Wen Ho, Chiao-Yun Chen, Fang-Ming Chen, Jaw-Yuan Wang, Steve R. Rofer, Tian-Lu Cheng, Tung-Ho Wu
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/2b4dfddba7b744d18fb782d6aef7decf
Autor:
Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou, Yu-Ching Hsieh, Ya-Chi Chang, Hsiao-Chen Huang, Zhi-Qin Li, Yuan-Chin Hsieh, I-Ju Chen, Bo-Cheng Huang, Yu-Cheng Su, Wen-Wei Lin, Hsin-Chieh Lin, Jui-I Chao, Shyng-Shiou F. Yuan, Yun-Ming Wang, Tian-Lu Cheng, Shey-Cherng Tzou
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-16 (2023)
Abstract Background CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG1 that is approved for treating rheumatoid arthritis. However, CTLA4Ig may induce adve
Externí odkaz:
https://doaj.org/article/04a6994390a54d96bd95a6eab38a44f9
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Engineering quantum states requires precise manipulations at the atomic level. Here, the authors use deep reinforcement learning to manipulate Ag adatoms on Ag surfaces, which combined with path planning algorithms enables autonomous atomic assembly.
Externí odkaz:
https://doaj.org/article/7bf6029542df4c3baecdb5278c8d57c8
Autor:
Yuan-Chin Hsieh, Jun-min Liao, Kuo-Hsiang Chuang, Kai-Wen Ho, Shih-Ting Hong, Hui-Ju Liu, Bo-Cheng Huang, I-Ju Chen, Yen-Ling Liu, Jaw-Yuan Wang, Hsiang-Lin Tsai, Yu-Cheng Su, Yen-Tseng Wang, Tian-Lu Cheng
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Humanization of mouse monoclonal antibodies (mAbs) is crucial for reducing their immunogenicity in humans. However, humanized mAbs often lose their binding affinities. Therefore, an in silico humanization method that can prevent t
Externí odkaz:
https://doaj.org/article/682be9e061ff404fb8b92628dae0d0c1
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Globally, obesity is a major health problem and can markedly increase the risk of various diseases, including type 2 diabetes mellitus, hypertension (HTN), dyslipidemia, and chronic kidney disease (CKD). The association of obesity-related parameters,
Externí odkaz:
https://doaj.org/article/9f819d2291a44b0c9c5546cfcfa07b3f
Autor:
Wen-Wei Lin, Yun-Chi Lu, Bo-Cheng Huang, Chih-Hung Chuang, Yi-An Cheng, I.-Ju Chen, Hui-Ju Liu, Kai-Wen Ho, Tzu-Yi Liao, En-Shuo Liu, Ting-Yi Wu, Long-Sen Chang, Shih-Ting Hong, Tian-Lu Cheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Canakinumab is a fully human monoclonal antibody that specifically neutralizes human interleukin (IL)-1β and has been approved by the US Food and Drug Administration for treating different types of autoinflammatory disorders such as cryopyr
Externí odkaz:
https://doaj.org/article/cbc2120056d34be588820d88d63a8a3e
Autor:
Michael J Campbell, Hope S Rugo, Chiun-Sheng Huang, Chun-Yen Lin, Jung-Tung Hung, I-Ju Chen, Shir-Hwa Ueng, Shin-Cheh Chen, Mu-Yi Chen, Yung-Chang Lin, Alice L Yu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/89c1a2bb641f4bd6abe6049e9723de97
Autor:
Kai-Wen Cheng, Chih-Hua Tseng, I.-Ju Chen, Bo-Cheng Huang, Hui-Ju Liu, Kai-Wen Ho, Wen-Wei Lin, Chih-Hung Chuang, Ming-Yii Huang, Yu-Lin Leu, Steve R. Roffler, Jaw-Yuan Wang, Yeh-Long Chen, Tian-Lu Cheng
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106115- (2022)
The bidirectional interaction between carcinogens and gut microbiota that contributes to colorectal cancer is complicated. Reactivation of carcinogen metabolites by microbial β-glucuronidase (βG) in the gut potentially plays an important role in co
Externí odkaz:
https://doaj.org/article/55f73cca8fc546a79e2f4bf887feeae5