Výsledky vyhledávání - "I. J. Rampil"

Ethanol directly depresses AMPA and NMDA glutamate currents in spinal cord motor neurons independent of actions on GABAA or glycine receptors

Autor: M Y, Wang, I J, Rampil, J J, Kendig

Publikováno v: The Journal of pharmacology and experimental therapeutics. 290(1)

Ethanol is a general anesthetic agent as defined by abolition of movement in response to noxious stimulation. This anesthetic endpoint is due to spinal anesthetic actions. This study was designed to test the hypothesis that ethanol acts directly on m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a55d0a34357a75f8c85b2ee36f383cf
https://pubmed.ncbi.nlm.nih.gov/10381800

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Cardiovascular actions of desflurane in normocarbic volunteers

Autor: R B, Weiskopf, M K, Cahalan, E I, Eger, N, Yasuda, I J, Rampil, P, Ionescu, S H, Lockhart, B H, Johnson, B, Freire, S, Kelley

Publikováno v: Anesthesia and analgesia. 73(2)

The cardiovascular actions of three concentrations of desflurane (formerly I-653), a new inhalation anesthetic, were examined in 12 unmedicated normocapnic, normothermic male volunteers. We compared the effects of 0.83, 1.24, and 1.66 MAC desflurane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::591e1b1dcb21162d4eacb1cac8451964
https://pubmed.ncbi.nlm.nih.gov/1854029

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Cardiovascular actions of desflurane with and without nitrous oxide during spontaneous ventilation in humans

Autor: R B, Weiskopf, M K, Cahalan, P, Ionescu, E I, Eger, N, Yasuda, S H, Lockhart, I J, Rampil, M, Laster, B, Freire, N, Peterson

Publikováno v: Anesthesia and analgesia. 73(2)

We investigated the cardiovascular actions of desflurane (formerly I-653) during spontaneous ventilation. We gave 0.8-0.9, 1.2-1.3, and 1.6-1.7 MAC desflurane in oxygen (n = 6) and in 60% nitrous oxide, balance oxygen (n = 6) to unmedicated healthy m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dcf4ef917d4544e8d1be90c2a5f18e97
https://pubmed.ncbi.nlm.nih.gov/1854031

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Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration

Autor: I J, Rampil, S H, Lockhart, M S, Zwass, N, Peterson, N, Yasuda, E I, Eger, R B, Weiskopf, M C, Damask

Publikováno v: Anesthesiology. 74(3)

Desflurane (formerly I-653) is a new inhalaticnal anesthetic with a promising pharmacokinetic profile that includes low solubility in blood and tissue, including fat. Since its lipid solubility is less than that of other volatile agents, it may have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3b590f4f6352d1622f0e22cce79e913
https://pubmed.ncbi.nlm.nih.gov/2001020

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Effect on outcome of prolonged exposure of patients to nitrous oxide

Autor: G H, Lampe, L Z, Wauk, J H, Donegan, L H, Pitts, R K, Jackler, L L, Litt, I J, Rampil, E I, Eger

Publikováno v: Anesthesia and analgesia. 71(6)

Prolonged (several days or repeated) exposure to nitrous oxide (N2O) can cause injury or death. To assess whether relatively prolonged anesthesia with N2O in normal patients might similarly cause untoward effects, we investigated whether the addition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd777d9dbc2689266bda1d5db0ec261f
https://pubmed.ncbi.nlm.nih.gov/2240628

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