Overcoming Bacteriophage Contamination in Bioprocessing: Strategies and Applications.

Autor: Zou X; Intensive Care Unit, Shenzhen Key Laboratory of Microbiology in Genomic Modification & Editing and Application, Shenzhen Institute of Translational Medicine, Medical Innovation Technology Transformation Center of Shenzhen Second People's Hospital, Shenzhen Univeristy Medical School, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, 518035, China.; Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), KAIST Institute for BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.; Synthetic Biology Research Center, Shenzhen University, Shenzhen, Guangdong, 518035, China., Mo Z; Department of Respiratory Diseases, Institute of Pediatrics, Shenzhen Children's Hospital, Shenzhen, Guangdong, 518026, China.; Department of Gastroenterology, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Taikang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China., Wang L; Department of Respiratory Diseases, Institute of Pediatrics, Shenzhen Children's Hospital, Shenzhen, Guangdong, 518026, China.; Department of Gastroenterology, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Taikang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China., Chen S; Intensive Care Unit, Shenzhen Key Laboratory of Microbiology in Genomic Modification & Editing and Application, Shenzhen Institute of Translational Medicine, Medical Innovation Technology Transformation Center of Shenzhen Second People's Hospital, Shenzhen Univeristy Medical School, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, 518035, China.; Synthetic Biology Research Center, Shenzhen University, Shenzhen, Guangdong, 518035, China.; Department of Gastroenterology, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, Ministry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Taikang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China., Lee SY; Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), KAIST Institute for BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, KAIST, Daejeon, 34141, Republic of Korea.; BioProcess Engineering Research Center and BioInformatics Research Center, KAIST, Daejeon, 34141, Republic of Korea.; Graduate School of Engineering Biology, KAIST, Daejeon, 34141, Republic of Korea.

Publikováno v: Small methods [Small Methods] 2024 Oct 02, pp. e2400932. Date of Electronic Publication: 2024 Oct 02.

The internal head protein Gp16 controls DNA ejection from the bacteriophage T7 virion

Autor: J S, Struthers-Schlinke, W P, Robins, P, Kemp, I J, Molineux

Publikováno v: Journal of molecular biology. 301(1)

A wild-type T7 virion ejects about 850 bp of the 40 kb genome into the bacterial cell by a transcription-independent process. Internalization of the remainder of the genome normally requires transcription. Inhibition of transcription-independent DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85956f9bdefba60b54479e26fdef28f9
https://pubmed.ncbi.nlm.nih.gov/10926491

Host-parasite interactions: recent developments in the genetics of abortive phage infections

Autor: I J, Molineux

Publikováno v: The New biologist. 3(3)

Recent progress towards the elucidation of the mechanisms of phage exclusion systems that lead to abortive infections is described. Abortive infections constitute model systems for the study of host-parasite interactions, but until the 1980s such stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7a5372d6e2ce0a7559731ce9d625089
https://pubmed.ncbi.nlm.nih.gov/1831658

Experimental Molecular Evolution of Bacteriophage T7

Autor: J. J. Bull, C. W. Cunningham, I. J. Molineux, M. R. Badgett, D. M. Hillis

Publikováno v: Evolution. 47:993

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ff4a0473ccb1fe508ca5bd5fb0e584c
https://doi.org/10.2307/2409971

Virulence Evolution via Pleiotropy in Vector‐Borne Plant Pathogens.

Autor: Woodruff, Elise, Hardy, Nate B.

Publikováno v: Ecology & Evolution (20457758); Dec2024, Vol. 14 Issue 12, p1-10, 10p