Zobrazeno 1 - 7
of 7
pro vyhledávání: '"I. J. Fraser"'
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:456-463
Capillary liquid chromatography (LC) using a 320 µm column and a flow rate of 10 µL/min has been coupled to an ion trap mass spectrometer using electrospray ionisation (ESI) to enable the rapid and effective identification of metabolites in urine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e53f2131294bc94effd5eacfb83d47b
https://doi.org/10.1002/(sici)1097-0231(19990315)13:5<456::aid-rcm508>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19990315)13:5<456::aid-rcm508>3.0.co
Autor:
I. M. Ismail, R. S. Plumb, I. J. Fraser, J. Ayrton, Gordon J. Dear, B. C. Sweatman, P. J. Mutch
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:2023-2030
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90767d55977b983805153116ddddf22d
https://doi.org/10.1002/(sici)1097-0231(19981230)12:24<2023::aid-rcm431>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19981230)12:24<2023::aid-rcm431>3.0.co
Autor:
I. J. Fraser, Keith W. Muir, John Posner, M. W. Lunnon, S. F. Hobbiger, Z. Hussein, Kennedy R. Lees
Publikováno v:
British Journal of Clinical Pharmacology. 41:505-511
1. This was a multi-centre, placebo controlled, randomized, dose-escalating design study in which five dosing regimens of 619C89/placebo were evaluated in 48 stroke patients. Loading infusions of 0.5, 1, 1.5, 2 and 2.5 mg kg-1 over 1 h were followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5036617c89b4b675c6d6395e00b1ef38
https://doi.org/10.1046/j.1365-2125.1996.03625.x
https://doi.org/10.1046/j.1365-2125.1996.03625.x
Autor:
Leslie V. Woodcock, I. J. Fraser
Publikováno v:
Molecular Simulation. 15:135-140
It is just 25 years since one of us submitted a Thesis describing molecular dynamics simulations which had been performed on the Atlas computer in London [1]. The Atlas occupied the whole ground floor of a large building at the London Institute of Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb54e36b14547597a740dde5e19fc1f8
https://doi.org/10.1080/08927029508024050
https://doi.org/10.1080/08927029508024050
Publikováno v:
Rapid communications in mass spectrometry : RCM. 13(23)
The methodology described demonstrates, for the first time, the feasibility of performing pharmacokinetic studies in the serially bled mouse model to support the early development of discovery compounds. Sample analysis, using capillary high performa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c49355229718a4360dd5547dbd862eb7
https://pubmed.ncbi.nlm.nih.gov/10567936
https://pubmed.ncbi.nlm.nih.gov/10567936
Publikováno v:
Rapid communications in mass spectrometry : RCM. 13(10)
Fast gradient capillary high performance liquid chromatography (HPLC) coupled to a mass spectrometer has been successfully used for the analysis of pharmaceutical compounds from biological matrices, in the femtogram on column range. In the work repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa1a1c32fe5d5c6ea1942e8cfcd0aacd
https://pubmed.ncbi.nlm.nih.gov/10353223
https://pubmed.ncbi.nlm.nih.gov/10353223
Publikováno v:
Rapid communications in mass spectrometry : RCM. 13(5)
Capillary liquid chromatography (LC) using a 320 microns column and a flow rate of 10 microL/min has been coupled to an ion trap mass spectrometer using electrospray ionisation (ESI) to enable the rapid and effective identification of metabolites in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad5ca0c4b08207fe215ab99cdeca0e56
https://pubmed.ncbi.nlm.nih.gov/10209877
https://pubmed.ncbi.nlm.nih.gov/10209877