Zobrazeno 1 - 10
of 469
pro vyhledávání: '"I. Hilgendorf"'
Autor:
J. Salchow, J. Mann, B. Koch, J. von Grundherr, W. Jensen, S. Elmers, L. A. Straub, E. Vettorazzi, G. Escherich, S. Rutkowski, S. Dwinger, C. Bergelt, M. Sokalska-Duhme, S. Bielack, G. Calaminus, K. Baust, C. F. Classen, C. Rössig, J. Faber, H. Faller, I. Hilgendorf, J. Gebauer, T. Langer, M. Metzler, S. Schuster, C. Niemeyer, A. Puzik, D. Reinhardt, U. Dirksen, A. Sander, M. Köhler, J. K. Habermann, C. Bokemeyer, A. Stein
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Improved, multimodal treatment strategies have been shown to increase cure rates in cancer patients. Those who survive cancer as a child, adolescent or young adult (CAYA), are at a higher risk for therapy-, or disease-related, lat
Externí odkaz:
https://doaj.org/article/b28e888c177b403f97dc1d02560d907e
Autor:
R. Casalegno-Garduño, C. Meier, A. Schmitt, A. Spitschak, I. Hilgendorf, S. Rohde, C. Hirt, M. Freund, B. M. Pützer, M. Schmitt
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Leukemic blasts overexpress immunogenic antigens, so-called leukemia-associated antigens like the receptor for hyaluronan acid-mediated motility (RHAMM). Persistent RHAMM expression and decreasing CD8+ T-cell responses to RHAMM in the framework of al
Externí odkaz:
https://doaj.org/article/e106b268c77744a5a0de1fd32a9bdd02
Autor:
Jacob D. Garritson, Jiabi Zhang, Alan Achenbach, Maroua Ferhat, Emile Eich, Chris J. Stubben, Paige L. Martinez, Anna R. Ibele, Keren I. Hilgendorf, Sihem Boudina
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Autocrine and paracrine signaling regulating adipogenesis in white adipose tissue remains largely unclear. Here we used single-cell RNA-sequencing (RNA-seq) and single nuclei RNA-sequencing (snRNA-seq) to identify markers of adipose progenit
Externí odkaz:
https://doaj.org/article/ea29e9686fc0499989d23cbee9f8bf05
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The primary cilium is a cellular sensory organelle found in most cells in our body. This includes adipocyte progenitor cells in our adipose tissue, a complex organ involved in energy storage, endocrine signaling, and thermogenesis. Numerous studies h
Externí odkaz:
https://doaj.org/article/706a4f9c43794bd18d748acfd0805f3c
Autor:
Ermelinda Porpiglia, Thach Mai, Peggy Kraft, Colin A. Holbrook, Antoine de Morree, Veronica D. Gonzalez, Keren I. Hilgendorf, Laure Frésard, Angelica Trejo, Sriram Bhimaraju, Peter K. Jackson, Wendy J. Fantl, Helen M. Blau
Publikováno v:
Porpiglia, E, Mai, T, Kraft, P, Holbrook, C A, de Morree, A, Gonzalez, V D, Hilgendorf, K I, Frésard, L, Trejo, A, Bhimaraju, S, Jackson, P K, Fantl, W J & Blau, H M 2022, ' Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration ', Cell Stem Cell, vol. 29, no. 12, pp. 1653-1668.e8 . https://doi.org/10.1016/j.stem.2022.10.009
Porpiglia, E 2022, ' Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration ', Cell Stem Cell, vol. 29, pp. 1-15 . https://doi.org/10.1016/j.stem.2022.10.009
Porpiglia, E 2022, ' Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration ', Cell Stem Cell, vol. 29, pp. 1-15 . https://doi.org/10.1016/j.stem.2022.10.009
SUMMARYIn aging, skeletal muscle strength and regenerative capacity declines due, in part, to functional impairment of muscle stem cells (MuSCs), yet the underlying mechanisms remain elusive. Here we capitalize on mass-cytometry to identify high CD47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04ad7c0435d5c85adc8688e5f4b2667
https://pure.au.dk/portal/da/publications/elevated-cd47-is-a-hallmark-of-dysfunctional-aged-muscle-stem-cells-that-can-be-targeted-to-augment-regeneration(c5ff0522-3d96-48d3-98c9-5ebe9d67b333).html
https://pure.au.dk/portal/da/publications/elevated-cd47-is-a-hallmark-of-dysfunctional-aged-muscle-stem-cells-that-can-be-targeted-to-augment-regeneration(c5ff0522-3d96-48d3-98c9-5ebe9d67b333).html
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Akademický článek
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Autor:
R Guillamat-Prats, D Hering, M Rami, C Haerdtner, D Santovito, P Rinne, S Pagano, N Nicolas Vuilleumier, S Schmid, A Janjic, W Enard, C Weber, L Maegdefessel, I Hilgendorf, S Steffens
Publikováno v:
European Heart Journal. 43
Atherosclerosis is a chronic and multifactorial disease accompanied by an imbalance between resolving and pro-inflammatory lipid mediators. Targeting lipid signaling might offer new therapeutical targets for improving the clinical outcome in cardiova
Autor:
M Middeke, A Simon, Anita Lawitschka, A Baumgartner, P Jäger, Jörg Halter, Daniel Wolff, Jann Arends, Hildegard T. Greinix, Gesine Bug, Silvan Klein, R Toenges, Christoph Schmid, I Hilgendorf, Eva-Maria Wagner-Drouet
Publikováno v:
Clinical Nutrition. 40:1571-1577
Summary Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is frequently associated with impaired oral intake and malnutrition, which potentially increases morbidity and mortality. Therefore, nutrition is one of the major challe
Autor:
Adelaida R. Palla, Keren I. Hilgendorf, Ann V. Yang, Jaclyn P. Kerr, Aaron C. Hinken, Janos Demeter, Peggy Kraft, Nancie A. Mooney, Nora Yucel, David M. Burns, Yu Xin Wang, Peter K. Jackson, Helen M. Blau
Publikováno v:
Nature Communications. 13
During aging, the regenerative capacity of muscle stem cells (MuSCs) decreases, diminishing the ability of muscle to repair following injury. We found that the ability of MuSCs to regenerate is regulated by the primary cilium, a cellular protrusion t