Zobrazeno 1 - 10
of 100
pro vyhledávání: '"I. Heinroth"'
Publikováno v:
Drug Development Research. 19:321-327
Trapidil and some other 5,7-disubstituted s-triazolo(1,5-a) pyrimidine derivatives (TD's: AR 12455, AR 12456, AR 12463, AR 12465), which have been shown to possess inhibitory effects on proliferative activity in cultured cells, influenced the cyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a85c54b01049b5d2be16ab1e640eeb2
https://doi.org/10.1002/ddr.430190310
https://doi.org/10.1002/ddr.430190310
Publikováno v:
British journal of pharmacology. 121(1)
1. Angiotensin II (AII) and the endothelins (ET) are known to be potent trophic stimuli in various cells including cardiomyocytes. In order to characterize further these effects we studied, in neonatal rat ventricular cardiomyocytes, the effects of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3ba99cf55df1b1b44566458469b816d
https://pubmed.ncbi.nlm.nih.gov/9146895
https://pubmed.ncbi.nlm.nih.gov/9146895
Publikováno v:
Cardiovascular research. 30(6)
The purpose of this study was to investigate the effects of prolonged arachidonic acid (AA) exposure on electrically induced fluctuations of cytosolic free Ca2+ concentration ([Ca2+]i) in cardiac myocytes and to identify intracellular biochemical eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1dbe0535b82318a6856223aae7d14a6
https://pubmed.ncbi.nlm.nih.gov/8746203
https://pubmed.ncbi.nlm.nih.gov/8746203
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 264(1)
The mechanism by which thromboxane A2 (TXA2) causes its detrimental actions on the myocardium during ischemia and reperfusion injury is unknown. The present study was designed to investigate the influence of U46619, a stable TXA2 analog, on intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::138cb6493fde598a478493fc6005d577
https://pubmed.ncbi.nlm.nih.gov/8423535
https://pubmed.ncbi.nlm.nih.gov/8423535
Publikováno v:
Klinische Wochenschrift. 61:187-191
Ten healthy volunteers daily received 30 ml linseed oil for 4 weeks in addition to the "normal" diet. The influence of linseed oil diet on the fatty acid pattern of plasma phospholipids and thromboxane formation in platelets was investigated. The fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6f5d1ef04ae243bbfe411db399ac58
https://doi.org/10.1007/bf01488973
https://doi.org/10.1007/bf01488973
Autor:
P, Hoffmann, C, Taube, I, Heinroth-Hoffmann, A, Fahr, J, Beitz, W, Förster, W S, Poleshuk, C M, Markov
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 276(2)
The experiments were carried out in order to clarify the mechanisms of attenuation of hypertension development by means of diets enriched with polyunsaturated fatty acids (PUFA) in spontaneously hypertensive rats (SHR). Female SHR were fed a linoleic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4c2f392ed8abd28f86386f055691456
https://pubmed.ncbi.nlm.nih.gov/4051642
https://pubmed.ncbi.nlm.nih.gov/4051642
Autor:
I. Heinroth, P. Mentz, Giessler C, Klaus Pönicke, Werner Förster, W Rettkowski, Zehl U, H.-U. Block
Publikováno v:
Advances in Myocardiology ISBN: 9781475744439
All vasodilatory drugs reported in this chapter possess an antiaggregatory effect on platelets, some of them with a synergistic effect on prostacyclin-induced inhibition of aggregation. Thus, the question seems valid whether the antiaggregatory effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a92e12c846921894d86994ab5e448e48
https://doi.org/10.1007/978-1-4757-4441-5_52
https://doi.org/10.1007/978-1-4757-4441-5_52
Publikováno v:
Prostaglandins, leukotrienes, and medicine. 12(2)
The effects of four beta-adrenoceptor blocking agents on arachidonic acid (AA)-induced platelet aggregation and thromboxane (TX) formation in human and rabbit platelet-rich plasma (PRP) as well as their influence on prostaglandin endoperoxide analogu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc3368ab1dc1cb5cdc349b12cb45c31
https://pubmed.ncbi.nlm.nih.gov/6139824
https://pubmed.ncbi.nlm.nih.gov/6139824
Autor:
H U, Block, I, Heinroth, C, Giessler, K, Pönicke, P, Mentz, U, Zehl, W, Rettkowski, A, Dunemann, W, Förster
Publikováno v:
Biomedica biochimica acta. 42(2-3)
The influence of the antianginal drug trapidil on the biosynthesis of thromboxane A2 (TXA2) and/or prostacyclin (PGI2), metabolites of arachidonic acid (AA), was investigated in rabbit and human platelet rich plasma (PRP), in homogenates of rabbit sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae56f450c1fec6dedc35308cdda3a9da
https://pubmed.ncbi.nlm.nih.gov/6411078
https://pubmed.ncbi.nlm.nih.gov/6411078
Publikováno v:
Biomedica biochimica acta. 43(8-9)
Five selected trapidil derivatives (12456, 12460, 12463, 12464, 12465) inhibited the arachidonic acid(AA)- and prostaglandin endoperoxide analogue(U-46619)- induced platelet aggregation as well as the AA- induced thromboxane A2(TXA2) formation. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34af29efc4290a7493cce37e3a868d9d
https://pubmed.ncbi.nlm.nih.gov/6440555
https://pubmed.ncbi.nlm.nih.gov/6440555