Zobrazeno 1 - 10
of 95
pro vyhledávání: '"I. H. Stevenson"'
Publikováno v:
Clinical & Experimental Immunology. Dec1988, Vol. 74 Issue 3, p489-493. 5p.
Publikováno v:
British Journal of Clinical Pharmacology. 34:316-321
1. Plasma ethanol concentrations were measured in 24 male volunteers for 9 h after a single oral dose of 710 mg kg-1. 2. The rate of decline of the plasma ethanol concentration (k0; mean +/- s.d.), was 186 +/- 26 mg l-1 h-1. 3. In each individual, th
Autor:
I. H. Stevenson, M. J. Cullen, John Feely, William C. J. Collins, N. R. Peden, R. S. Macwalter, A. H. El Debani
Publikováno v:
British Journal of Clinical Pharmacology. 35:321-323
In a randomised placebo controlled study, two groups of six maturity onset diabetic patients stabilised on glipizide were given cimetidine (400 mg) or ranitidine (150 mg) 3 h before a standardised meal. In comparison with placebo, both cimetidine and
Publikováno v:
Journal of clinical pharmacology. 33(5)
This report concerns the development of an assessment* model (PharmTest)† for further evaluation by academic pharmacologists. The content area chosen for this model is the pharmacology of affective disorders. The components of the PharmTest system
Publikováno v:
Biochemical pharmacology. 40(4)
The present study reports the effect of postmortem delay on the in vitro modulation of the GABA A receptor by pentobarbitone in rat brain membranes
Publikováno v:
The Journal of pharmacy and pharmacology. 42(3)
The effect of temperature on the modulation of the GABAA receptor by barbiturates and steroids has been investigated in-vitro using a radioreceptor binding assay. Displaceable [3H]muscimol binding to a crude membrane preparation from rat cerebral cor
Autor:
B F Tregaskis, I H Stevenson
Publikováno v:
British medical bulletin. 46(1)
All practising clinicians will be aware of the increased number of elderly patients requiring drug treatment as the proportion of people over the age of 65 increases in our Western society. The elderly as a group have much to benefit from modern drug
Publikováno v:
Human Toxicology. 2:149-153
1 The relationship between plasma chlorpropamide concentration and thyroid function was examined in 87 maturity onset diabetic patients receiving chronic therapy. 2 Although plasma chlorpropamide concentration was weakly negatively correlated with se
Publikováno v:
Journal of Pharmacy and Pharmacology. 39:378-383
The two enantiomers ((R)- and (S)-) of propranolol glycol, a metabolite of propranolol, have been synthesized, and their effects upon the β-adrenoceptor studied by two methods. The ability of these compounds to antagonize the inotropic actions of is
Autor:
J. Crooks, I. H. Stevenson
Publikováno v:
Age and Ageing. 10:73-80
There is now a considerable body of evidence to indicate that response to many drugs changes as people ages. As a result, interest has increased in recent years in the investigation of mechanisms contributing to altered drug responsiveness with age.