Zobrazeno 1 - 10
of 649
pro vyhledávání: '"I. Griffiths"'
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract Fibroblast growth factors (FGFs) control various cellular functions through fibroblast growth factor receptor (FGFR) activation, including proliferation, differentiation, migration, and survival. FGFR amplification in ER + breast cancer pati
Externí odkaz:
https://doaj.org/article/9d8a1a28a88c466a86db64bb029178e3
Autor:
J. M. Lavallee, M. Chomel, N. Alvarez Segura, F. de Castro, T. Goodall, M. Magilton, J. M. Rhymes, M. Delgado-Baquerizo, R. I. Griffiths, E. M. Baggs, T. Caruso, F. T. de Vries, M. Emmerson, D. Johnson, R. D. Bardgett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Soil microbial communities are dominated by a relatively small number of taxa that may play outsized roles in ecosystem functioning, yet little is known about their capacities to resist and recover from climate extremes such as drought, or h
Externí odkaz:
https://doaj.org/article/cd86d58e5ba548a8914cbacf7673ad15
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Tumors are comprised of subpopulations of cancer cells that harbor distinct genetic profiles and phenotypes that evolve over time and during treatment. By reconstructing the course of cancer evolution, we can understand the acquisition of th
Externí odkaz:
https://doaj.org/article/32809e00495645f1b0e0865e48743292
Autor:
Rena Emond, Jason I. Griffiths, Vince Kornél Grolmusz, Aritro Nath, Jinfeng Chen, Eric F. Medina, Rachel S. Sousa, Timothy Synold, Frederick R. Adler, Andrea H. Bild
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The interplay of positive and negative interactions between drug-sensitive and resistant cells influences the effectiveness of treatment in heterogeneous cancer cell populations. Here, we study interactions between estrogen receptor-positive
Externí odkaz:
https://doaj.org/article/ace0baddb0824ad0a9092e60d8e05400
Autor:
Clare H. Robinson, Jonathan P. Ritson, Danielle M. Alderson, Ashish A. Malik, Robert I. Griffiths, Andreas Heinemeyer, Angela V. Gallego-Sala, Anne Quillet, Bjorn J.M. Robroek, Chris Evans, Dave M. Chandler, David R. Elliott, Emma L. Shutttleworth, Erik A. Lilleskov, Ezra Kitson, Filipa Cox, Fred Worrall, Gareth D. Clay, Ian Crosher, Jennifer Pratscher, Jon Bird, Jonathan Walker, Lisa R. Belyea, Marc G. Dumont, Nichole G.A. Bell, Rebekka R.E. Artz, Richard D. Bardgett, Roxane Andersen, Simon M. Hutchinson, Susan E. Page, Tim J. Thom, William Burn, Martin G. Evans
Publikováno v:
Mires and Peat, Vol 29, Iss 02, Pp 1-36 (2023)
Globally, major efforts are being made to restore peatlands to maximise their resilience to anthropogenic climate change, which puts continuous pressure on peatland ecosystems and modifies the geography of the environmental envelope that underpins pe
Externí odkaz:
https://doaj.org/article/271ed4995dde4be88e11c018766b1671
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Recent advances in single cell RNA sequencing (scRNA-seq) technologies have been invaluable in the study of the diversity of cancer cells and the tumor microenvironment. While scRNA-seq platforms allow processing of a high number of cells, uneven rea
Externí odkaz:
https://doaj.org/article/5aaf248867914b4e933380b0059d5619
Autor:
J. Drewer, M. M. Leduning, R. I. Griffiths, T. Goodall, P. E. Levy, N. Cowan, E. Comynn-Platt, G. Hayman, J. Sentian, N. Majalap, U. M. Skiba
Publikováno v:
Biogeosciences, Vol 18, Pp 1559-1575 (2021)
In Southeast Asia, oil palm (OP) plantations have largely replaced tropical forests. The impact of this shift in land use on greenhouse gas (GHG) fluxes remains highly uncertain, mainly due to a relatively small pool of available data. The aim of thi
Externí odkaz:
https://doaj.org/article/773d9b33d4dc44379e3cfd0152903f54
Autor:
Kate M. Buckeridge, Kelly E. Mason, Niall P. McNamara, Nick Ostle, Jeremy Puissant, Tim Goodall, Robert I. Griffiths, Andrew W. Stott, Jeanette Whitaker
Publikováno v:
Communications Earth & Environment, Vol 1, Iss 1, Pp 1-9 (2020)
Microbial necromass recycling, which can influence soil carbon stabilization, is controlled by microbial growth and precipitation, as indicated by stable isotope tracing and indicator species analysis in a range of UK grasslands.
Externí odkaz:
https://doaj.org/article/c59357c554f84f8a86ed4f21238c51d2
Autor:
Robert I. Griffiths, Rafael Cavalcante, Alysha M. McGovern, Aparna Bhave, Liesl M. Hargens, Craig A. Solid, Amit P. Amin
Publikováno v:
American Heart Journal. 262:20-28
Autor:
Paul B. L. George, David B. Fidler, Joy D. Van Nostrand, Jonathan A. Atkinson, Sacha J. Mooney, Simon Creer, Robert I. Griffiths, James E. McDonald, David A. Robinson, Davey L. Jones
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Soil organic matter is composed of a variety of carbon (C) forms. However, not all forms are equally accessible to soil microorganisms. Deprivation of C inputs will cause changes in the physical and microbial community structures of soils; yet the tr
Externí odkaz:
https://doaj.org/article/43f290fe6750486389669fb13797a337